Patterns of Diversity in HIV-Related Loci among Subspecies of Chimpanzee: Concordance at CCR5 and Differences at CXCR4 and CX3CR1

Human immunodeficiency virus type 1 (HIV-1) arose in humans via zoonotic transmissions of simian immunodeficiency viruses (SIVcpz) from common chimpanzees, Pan troglodytes. Despite the close relatedness of the two viruses and their hosts, we do not yet understand what causes SIVcpz to be nonpathogen...

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Veröffentlicht in:	Molecular biology and evolution 2009-04, Vol.26 (4), p.719-727
Hauptverfasser:	MacFie, T.S., Nerrienet, E., de Groot, N.G., Bontrop, R.E., Mundy, N.I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals HIV Infections - genetics Human immunodeficiency virus 1 Humans Pan troglodytes Pan troglodytes - classification Pan troglodytes - genetics Pan troglodytes troglodytes Receptors, CCR5 - genetics Receptors, Chemokine - genetics Receptors, CXCR4 - genetics
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