Fos Expression in CRF-containing Neurons in the Rat Paraventricular Nucleus after Central Administration of Neuromedin U
We examined the effects of centrally administered neuromedin U (NMU) on corticotrophin-releasing factor (CRF)-containing neurons in the hypothalamic paraventricular nucleus (PVN) of rats, using double immunohistochemistry for CRF and Fos. Almost all CRF-containing neurons in the parvocellular divisi...
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| Veröffentlicht in: | Stress (Amsterdam, Netherlands) Netherlands), 2004-06, Vol.7 (2), p.109-112 |
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| container_title | Stress (Amsterdam, Netherlands) |
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| creator | Yokota, Makoto Ozaki, Yumi Sakamoto, Fumihiko Yamada, Seiji Saito, Jun Fujihara, Hiroaki Ueta, Yoichi |
| description | We examined the effects of centrally administered neuromedin U (NMU) on corticotrophin-releasing factor (CRF)-containing neurons in the hypothalamic paraventricular nucleus (PVN) of rats, using double immunohistochemistry for CRF and Fos. Almost all CRF-containing neurons in the parvocellular divisions of the PVN expressed Fos-like immunoreactivity 90 min after intracerebroventricular administration of NMU (3 nmol/rat). This results suggest the possibility that central NMU may be involved in stress-induced activation of CRF-containing neurons in the PVN. |
| doi_str_mv | 10.1080/10253890410001727370 |
| format | Article |
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Almost all CRF-containing neurons in the parvocellular divisions of the PVN expressed Fos-like immunoreactivity 90 min after intracerebroventricular administration of NMU (3 nmol/rat). 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Almost all CRF-containing neurons in the parvocellular divisions of the PVN expressed Fos-like immunoreactivity 90 min after intracerebroventricular administration of NMU (3 nmol/rat). This results suggest the possibility that central NMU may be involved in stress-induced activation of CRF-containing neurons in the PVN.</description><subject>Animals</subject><subject>Corticotropin-Releasing Hormone - metabolism</subject><subject>CRF</subject><subject>Fos</subject><subject>Injections, Intraventricular</subject><subject>Male</subject><subject>Neuromedin U</subject><subject>Neurons - metabolism</subject><subject>Neuropeptides - administration & dosage</subject><subject>Neuropeptides - pharmacology</subject><subject>Paraventricular Hypothalamic Nucleus</subject><subject>Paraventricular nucleus</subject><subject>Proto-Oncogene Proteins c-fos - metabolism</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Time Factors</subject><issn>1025-3890</issn><issn>1607-8888</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF2L1TAQhoso7of-A5FceVedNB9tb5TlsMcVllUW9zpM09STJU2OSaq7_96Uc0AE0dwkMM88mXmr6hWFtxQ6eEehEazrgVMAoG3TshaeVKdUQlt35Twt74LUK3NSnaV0XzgpgD-vTqgQtOkEP60etiGRy4d9NCnZ4In1ZHO7rXXwGa23_hu5MUsMPq2VvDPkFjP5ghF_GJ-j1YvDSG4W7cySCE7ZRLJZK-jIxTgXQyrvvJrDdFDNZiyquxfVswldMi-P93l1t738urmqrz9__LS5uK417yDXoxygjAqdkEZySscRDUeEYewbjYbJoZFMNr3QZR8tRi0Y43wYegAUlHF2Xr05ePcxfF9Mymq2SRvn0JuwJCVbaLqeNwXkB1DHkFI0k9pHO2N8VBTUmrj6W-Kl7fXRvwxltd9Nx4gL8OEAWD-FOOPPEN2oMj66EKeIXtuk2H--eP-HYWfQ5Z3GaNR9WKIv8f17xl8EtKKz</recordid><startdate>200406</startdate><enddate>200406</enddate><creator>Yokota, Makoto</creator><creator>Ozaki, Yumi</creator><creator>Sakamoto, Fumihiko</creator><creator>Yamada, Seiji</creator><creator>Saito, Jun</creator><creator>Fujihara, Hiroaki</creator><creator>Ueta, Yoichi</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200406</creationdate><title>Fos Expression in CRF-containing Neurons in the Rat Paraventricular Nucleus after Central Administration of Neuromedin U</title><author>Yokota, Makoto ; Ozaki, Yumi ; Sakamoto, Fumihiko ; Yamada, Seiji ; Saito, Jun ; Fujihara, Hiroaki ; Ueta, Yoichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c480t-d6b01280856e6411ddae4aa0bd92cae36b2636295c285c5dc53344bb900a51343</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Animals</topic><topic>Corticotropin-Releasing Hormone - metabolism</topic><topic>CRF</topic><topic>Fos</topic><topic>Injections, Intraventricular</topic><topic>Male</topic><topic>Neuromedin U</topic><topic>Neurons - metabolism</topic><topic>Neuropeptides - administration & dosage</topic><topic>Neuropeptides - pharmacology</topic><topic>Paraventricular Hypothalamic Nucleus</topic><topic>Paraventricular nucleus</topic><topic>Proto-Oncogene Proteins c-fos - metabolism</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yokota, Makoto</creatorcontrib><creatorcontrib>Ozaki, Yumi</creatorcontrib><creatorcontrib>Sakamoto, Fumihiko</creatorcontrib><creatorcontrib>Yamada, Seiji</creatorcontrib><creatorcontrib>Saito, Jun</creatorcontrib><creatorcontrib>Fujihara, Hiroaki</creatorcontrib><creatorcontrib>Ueta, Yoichi</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Stress (Amsterdam, Netherlands)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yokota, Makoto</au><au>Ozaki, Yumi</au><au>Sakamoto, Fumihiko</au><au>Yamada, Seiji</au><au>Saito, Jun</au><au>Fujihara, Hiroaki</au><au>Ueta, Yoichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fos Expression in CRF-containing Neurons in the Rat Paraventricular Nucleus after Central Administration of Neuromedin U</atitle><jtitle>Stress (Amsterdam, Netherlands)</jtitle><addtitle>Stress</addtitle><date>2004-06</date><risdate>2004</risdate><volume>7</volume><issue>2</issue><spage>109</spage><epage>112</epage><pages>109-112</pages><issn>1025-3890</issn><eissn>1607-8888</eissn><abstract>We examined the effects of centrally administered neuromedin U (NMU) on corticotrophin-releasing factor (CRF)-containing neurons in the hypothalamic paraventricular nucleus (PVN) of rats, using double immunohistochemistry for CRF and Fos. Almost all CRF-containing neurons in the parvocellular divisions of the PVN expressed Fos-like immunoreactivity 90 min after intracerebroventricular administration of NMU (3 nmol/rat). This results suggest the possibility that central NMU may be involved in stress-induced activation of CRF-containing neurons in the PVN.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>15512854</pmid><doi>10.1080/10253890410001727370</doi><tpages>4</tpages></addata></record> |
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| ispartof | Stress (Amsterdam, Netherlands), 2004-06, Vol.7 (2), p.109-112 |
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| subjects | Animals Corticotropin-Releasing Hormone - metabolism CRF Fos Injections, Intraventricular Male Neuromedin U Neurons - metabolism Neuropeptides - administration & dosage Neuropeptides - pharmacology Paraventricular Hypothalamic Nucleus Paraventricular nucleus Proto-Oncogene Proteins c-fos - metabolism Rats Rats, Wistar Time Factors |
| title | Fos Expression in CRF-containing Neurons in the Rat Paraventricular Nucleus after Central Administration of Neuromedin U |
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