Immediate improvement in coronary flow reserve after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy

Objectives:To examine whether percutaneous alcohol septal ablation affects coronary flow reserve (CFR) in patients with hypertrophic cardiomyopathy (HCM).Methods:CFR was measured immediately before and after septal ablation in patients with symptomatic obstructive HCM. CFR was also obtained in norma...

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Veröffentlicht in:	Heart (British Cardiac Society) 2009-04, Vol.95 (7), p.564-569
Hauptverfasser:	Jaber, W A, Yang, E H, Nishimura, R A, Sorajja, P, Rihal, C S, Elesber, A, Eeckhout, E, Lerman, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Aged Alcohol Biological and medical sciences Cardiology. Vascular system Cardiomyopathy Cardiomyopathy, Hypertrophic - diagnostic imaging Cardiomyopathy, Hypertrophic - physiopathology Cardiomyopathy, Hypertrophic - therapy Cardiovascular disease Case-Control Studies Catheter Ablation - methods Chi-Square Distribution Coronary Circulation - physiology Coronary vessels Echocardiography, Doppler Ethanol - administration & dosage Female Heart Heart attacks Heart Septum Humans Integrated software Male Medical sciences Middle Aged Myocarditis. Cardiomyopathies Pain Prospective Studies Treatment Outcome Velocity
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Zusammenfassung:	Objectives:To examine whether percutaneous alcohol septal ablation affects coronary flow reserve (CFR) in patients with hypertrophic cardiomyopathy (HCM).Methods:CFR was measured immediately before and after septal ablation in patients with symptomatic obstructive HCM. CFR was also obtained in normal subjects (NL) for comparison.Results:Patients with HCM (n = 11), compared with NL (n = 22), had a lower mean (SD) baseline CFR (1.96 (0.5) vs 3.0 (0.7), p
ISSN:	1355-6037 1468-201X
DOI:	10.1136/hrt.2008.148239