Fundus pigment distribution in rhesus monkeys
There is growing evidence for an interaction among fundus pigmentation, character, geography and the function and structure of the outer retina. We examined three inbred groups of rhesus macaques (132 eyes) including all ages. One was a smaller (18 eyes) group. Coat colors were variations of brown–t...
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| Veröffentlicht in: | Veterinary ophthalmology 2004-11, Vol.7 (6), p.391-396 |
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| creator | Dawson, W.W Jeffery, G Dawson, J.C Kessler, M.J Rodriguez, J Westergaards, G.C |
| description | There is growing evidence for an interaction among fundus pigmentation, character, geography and the function and structure of the outer retina. We examined three inbred groups of rhesus macaques (132 eyes) including all ages. One was a smaller (18 eyes) group. Coat colors were variations of brown–tan however, the smaller group had lighter ‘golden’ coats and colors. Fundus images were classified for pigmentation and its geographic distribution. In golden‐coated animals there was bias toward nasal fundus hypopigmentation with the optic disk as a watershed demarcation zone, which extended in the superior–inferior direction. Temporal fundus hypopigmentation did not occur in the absence of nasal hypopigmentation. More common, darker coated samples showed a characteristic diffuse fundus pigmentation. There was no evidence for albinism or large variations in macular pigmentation. Rhesus monkeys can exhibit geographically controlled genetic development of fundus pigmentation. Hypopigmentation provides for access to the choroidal infrastructure. |
| doi_str_mv | 10.1111/j.1463-5224.2004.04042.x |
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We examined three inbred groups of rhesus macaques (132 eyes) including all ages. One was a smaller (18 eyes) group. Coat colors were variations of brown–tan however, the smaller group had lighter ‘golden’ coats and colors. Fundus images were classified for pigmentation and its geographic distribution. In golden‐coated animals there was bias toward nasal fundus hypopigmentation with the optic disk as a watershed demarcation zone, which extended in the superior–inferior direction. Temporal fundus hypopigmentation did not occur in the absence of nasal hypopigmentation. More common, darker coated samples showed a characteristic diffuse fundus pigmentation. There was no evidence for albinism or large variations in macular pigmentation. Rhesus monkeys can exhibit geographically controlled genetic development of fundus pigmentation. Hypopigmentation provides for access to the choroidal infrastructure.</description><subject>albino</subject><subject>animal age</subject><subject>animal development</subject><subject>Animals</subject><subject>development</subject><subject>Eye Color - physiology</subject><subject>Female</subject><subject>fundus</subject><subject>Fundus Oculi</subject><subject>hairs</subject><subject>inbred lines</subject><subject>Macaca mulatta</subject><subject>Macaca mulatta - anatomy & histology</subject><subject>Macaca mulatta - genetics</subject><subject>Male</subject><subject>melanin</subject><subject>monkey</subject><subject>monkeys</subject><subject>nasal cavity</subject><subject>Ophthalmoscopy - veterinary</subject><subject>pigmentation</subject><subject>Pigmentation - genetics</subject><subject>Pigmentation - physiology</subject><subject>primate</subject><subject>retina</subject><subject>zoogeography</subject><issn>1463-5216</issn><issn>1463-5224</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1v1DAQhi0EoqXwFyAnbgnj8UfiCxKq6IJUtaBSQFwsx3aKt5tksTdi99_jbVbLEeYyI80zr-WHkIJCRXO9WVaUS1YKRF4hAK-AA8dq-4icHhePjzOVJ-RZSksAYALqp-SECkEpNnBKyotpcFMq1uGu98OmcCFtYminTRiHIgxF_OlTXvfjcO936Tl50plV8i8O_YzcXrz_cv6hvLxefDx_d1laLhSWQhlsjWtaa2WLjnJUyGvJjALnWe2sqxWi6aSlXnnJhbCuE9Yw4ZynrmFn5PWcu47jr8mnje5Dsn61MoMfp6RlDcibBv4JUsU5Ngwz2MygjWNK0Xd6HUNv4k5T0Huneqn3uvRend471Q9O9Tafvjy8MbW9d38PDxIz8HYGfoeV3_13sP56_elhzAHlHJDl--0xwMT7_FNWC_3taqGvfnxfiM9K6ZvMv5r5zoza3MWQ9O0NAmUAStYokf0BXGmdOQ</recordid><startdate>200411</startdate><enddate>200411</enddate><creator>Dawson, W.W</creator><creator>Jeffery, G</creator><creator>Dawson, J.C</creator><creator>Kessler, M.J</creator><creator>Rodriguez, J</creator><creator>Westergaards, G.C</creator><general>Blackwell Science Ltd</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>200411</creationdate><title>Fundus pigment distribution in rhesus monkeys</title><author>Dawson, W.W ; Jeffery, G ; Dawson, J.C ; Kessler, M.J ; Rodriguez, J ; Westergaards, G.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4592-59a2bad8bcc6b2d142924763a90de37dcd7922af6c1e9e6455cdf5ca35dde1d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>albino</topic><topic>animal age</topic><topic>animal development</topic><topic>Animals</topic><topic>development</topic><topic>Eye Color - physiology</topic><topic>Female</topic><topic>fundus</topic><topic>Fundus Oculi</topic><topic>hairs</topic><topic>inbred lines</topic><topic>Macaca mulatta</topic><topic>Macaca mulatta - anatomy & histology</topic><topic>Macaca mulatta - genetics</topic><topic>Male</topic><topic>melanin</topic><topic>monkey</topic><topic>monkeys</topic><topic>nasal cavity</topic><topic>Ophthalmoscopy - veterinary</topic><topic>pigmentation</topic><topic>Pigmentation - genetics</topic><topic>Pigmentation - physiology</topic><topic>primate</topic><topic>retina</topic><topic>zoogeography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dawson, W.W</creatorcontrib><creatorcontrib>Jeffery, G</creatorcontrib><creatorcontrib>Dawson, J.C</creatorcontrib><creatorcontrib>Kessler, M.J</creatorcontrib><creatorcontrib>Rodriguez, J</creatorcontrib><creatorcontrib>Westergaards, G.C</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dawson, W.W</au><au>Jeffery, G</au><au>Dawson, J.C</au><au>Kessler, M.J</au><au>Rodriguez, J</au><au>Westergaards, G.C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fundus pigment distribution in rhesus monkeys</atitle><jtitle>Veterinary ophthalmology</jtitle><addtitle>Vet Ophthalmol</addtitle><date>2004-11</date><risdate>2004</risdate><volume>7</volume><issue>6</issue><spage>391</spage><epage>396</epage><pages>391-396</pages><issn>1463-5216</issn><eissn>1463-5224</eissn><abstract>There is growing evidence for an interaction among fundus pigmentation, character, geography and the function and structure of the outer retina. We examined three inbred groups of rhesus macaques (132 eyes) including all ages. One was a smaller (18 eyes) group. Coat colors were variations of brown–tan however, the smaller group had lighter ‘golden’ coats and colors. Fundus images were classified for pigmentation and its geographic distribution. In golden‐coated animals there was bias toward nasal fundus hypopigmentation with the optic disk as a watershed demarcation zone, which extended in the superior–inferior direction. Temporal fundus hypopigmentation did not occur in the absence of nasal hypopigmentation. More common, darker coated samples showed a characteristic diffuse fundus pigmentation. There was no evidence for albinism or large variations in macular pigmentation. Rhesus monkeys can exhibit geographically controlled genetic development of fundus pigmentation. Hypopigmentation provides for access to the choroidal infrastructure.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Ltd</pub><pmid>15511280</pmid><doi>10.1111/j.1463-5224.2004.04042.x</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | albino animal age animal development Animals development Eye Color - physiology Female fundus Fundus Oculi hairs inbred lines Macaca mulatta Macaca mulatta - anatomy & histology Macaca mulatta - genetics Male melanin monkey monkeys nasal cavity Ophthalmoscopy - veterinary pigmentation Pigmentation - genetics Pigmentation - physiology primate retina zoogeography |
| title | Fundus pigment distribution in rhesus monkeys |
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