Simultaneous assay of glucose, lactate, L-glutamate and hypoxanthine levels in a rat striatum using enzyme electrodes based on neutral red-doped silica nanoparticles

An electrochemical method suitable for the simultaneous measurement of cerebral glucose, lactate, L-glutamate and hypoxanthine concentrations from in vivo microdialysis sampling has been successfully performed for the first time using a neutral red-doped silica (NRDS) nanoparticle-derived enzyme sen...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2004-10, Vol.380 (4), p.637-642
Hauptverfasser:	Zhang, Fen-Fen, Wan, Qiao, Li, Chen-Xin, Wang, Xiao-Li, Zhu, Zi-Qiang, Xian, Yue-Zhong, Jin, Li-Tong, Yamamoto, Katsunobu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biosensing Techniques - instrumentation Biosensing Techniques - methods Electrochemistry Electrodes Glucose - analysis Glucose - metabolism Glutamic Acid - analysis Glutamic Acid - metabolism Hydrogen-Ion Concentration Hypoxanthine - analysis Hypoxanthine - metabolism Lactic Acid - analysis Lactic Acid - metabolism Microscopy, Electron, Transmission Nanotechnology Neostriatum - metabolism Neutral Red Oxidoreductases - metabolism Particle Size Rats Silicon Dioxide Temperature Time Factors
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