Wide variation in cardiopulmonary resuscitation interruption intervals among commercially available automated external defibrillators may affect survival despite high defibrillation efficacy
OBJECTIVE:Recent studies have associated interruptions of cardiopulmonary resuscitation imposed by automated external defibrillators (AEDs) with poor resuscitation outcome. In particular, the “hands-off” interval between precordial compressions and subsequent defibrillation shock has been implicated...
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| Veröffentlicht in: | Critical care medicine 2004-09, Vol.32 (9 Suppl), p.S421-S424 |
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| container_issue | 9 Suppl |
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| container_title | Critical care medicine |
| container_volume | 32 |
| creator | Snyder, David Morgan, Carl |
| description | OBJECTIVE:Recent studies have associated interruptions of cardiopulmonary resuscitation imposed by automated external defibrillators (AEDs) with poor resuscitation outcome. In particular, the “hands-off” interval between precordial compressions and subsequent defibrillation shock has been implicated. We sought to determine the range of variation among current-generation AEDs with respect to this characteristic.
MEASUREMENTS:Seven AEDs from six manufacturers were characterized via stopwatch and arrhythmia simulator with respect to the imposed hands-off interval. All AEDs were equipped with new batteries, and measurements were repeated five times for each AED.
MAIN RESULTS:A wide variation in the hands-off interval between precordial compressions and shock delivery was observed, ranging from 5.2 to 28.4 secs, with only one AED achieving an interruption of |
| doi_str_mv | 10.1097/01.CCM.0000134265.35871.2B |
| format | Article |
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MEASUREMENTS:Seven AEDs from six manufacturers were characterized via stopwatch and arrhythmia simulator with respect to the imposed hands-off interval. All AEDs were equipped with new batteries, and measurements were repeated five times for each AED.
MAIN RESULTS:A wide variation in the hands-off interval between precordial compressions and shock delivery was observed, ranging from 5.2 to 28.4 secs, with only one AED achieving an interruption of <10 secs. Laboratory and clinical data suggest that this range of variation could be responsible for a more than two-fold variation in patient resuscitation success, an effect that far exceeds any defibrillation efficacy differences that may hypothetically exist.
CONCLUSIONS:In addition to defibrillation waveform and dose, researchers should consider the hands-off cardiopulmonary resuscitation interruption interval between cardiopulmonary resuscitation and subsequent defibrillation shock to be an important covariate of outcome in resuscitation studies. Defibrillator design should minimize this interval to avoid potential adverse consequences on patient survival.</description><identifier>ISSN: 0090-3493</identifier><identifier>EISSN: 1530-0293</identifier><identifier>DOI: 10.1097/01.CCM.0000134265.35871.2B</identifier><identifier>PMID: 15508671</identifier><identifier>CODEN: CCMDC7</identifier><language>eng</language><publisher>Hagerstown, MD: by the Society of Critical Care Medicine and Lippincott Williams & Wilkins</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Cardiopulmonary Resuscitation ; Electric Countershock - instrumentation ; Equipment Design ; Heart Arrest - therapy ; Humans ; Intensive care medicine ; Medical sciences ; Treatment Outcome</subject><ispartof>Critical care medicine, 2004-09, Vol.32 (9 Suppl), p.S421-S424</ispartof><rights>2004 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3056-7e664020f095259d64759946447141712082c854de5d17ec3503deb7b56aa0903</citedby><cites>FETCH-LOGICAL-c3056-7e664020f095259d64759946447141712082c854de5d17ec3503deb7b56aa0903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23930,23931,25140,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16100828$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15508671$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Snyder, David</creatorcontrib><creatorcontrib>Morgan, Carl</creatorcontrib><title>Wide variation in cardiopulmonary resuscitation interruption intervals among commercially available automated external defibrillators may affect survival despite high defibrillation efficacy</title><title>Critical care medicine</title><addtitle>Crit Care Med</addtitle><description>OBJECTIVE:Recent studies have associated interruptions of cardiopulmonary resuscitation imposed by automated external defibrillators (AEDs) with poor resuscitation outcome. In particular, the “hands-off” interval between precordial compressions and subsequent defibrillation shock has been implicated. We sought to determine the range of variation among current-generation AEDs with respect to this characteristic.
MEASUREMENTS:Seven AEDs from six manufacturers were characterized via stopwatch and arrhythmia simulator with respect to the imposed hands-off interval. All AEDs were equipped with new batteries, and measurements were repeated five times for each AED.
MAIN RESULTS:A wide variation in the hands-off interval between precordial compressions and shock delivery was observed, ranging from 5.2 to 28.4 secs, with only one AED achieving an interruption of <10 secs. Laboratory and clinical data suggest that this range of variation could be responsible for a more than two-fold variation in patient resuscitation success, an effect that far exceeds any defibrillation efficacy differences that may hypothetically exist.
CONCLUSIONS:In addition to defibrillation waveform and dose, researchers should consider the hands-off cardiopulmonary resuscitation interruption interval between cardiopulmonary resuscitation and subsequent defibrillation shock to be an important covariate of outcome in resuscitation studies. Defibrillator design should minimize this interval to avoid potential adverse consequences on patient survival.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cardiopulmonary Resuscitation</subject><subject>Electric Countershock - instrumentation</subject><subject>Equipment Design</subject><subject>Heart Arrest - therapy</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Medical sciences</subject><subject>Treatment Outcome</subject><issn>0090-3493</issn><issn>1530-0293</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpNkVuP0zAQhSMEYsvCX0AWEryljONbwxtbcZMW8QLi0Zo6k63BSYqdZOmf47fhXlDxi2XpOz4z5xTFCw5LDrV5DXy5Xn9eQj5cyEqrpVArw5fVzYNiwZWAEqpaPCwWADWUQtbiqniS0o-MS2XE4-KKKwUrbfii-PPdN8RmjB5HP_TM98xhbPywm0I39Bj3LFKakvPjP2CkGKfd5TFjSAwzfMfc0HUUnccQ9gxn9AE3gRhO49DhSA2j31nQY2ANtX4TfQg4DjGxDjPftuRGlqY4-_mIpJ0fiW393fZ__mBMbesduv3T4lGb7enZ-b4uvr1_93X9sbz98uHT-u1t6QQoXRrSWkIFLdSqUnWjpVF1LbWUhktueAWryq2UbEg13JATCkRDG7NRGjGHKK6LV6d_d3H4NVEabeeTozxOT8OUrDbATaVWGXxzAl0cUorU2l30XY7RcrCH9ixwm9uzl_bssT1b3WTx87PLtOmouUjPdWXg5RnA5DC0EXvn04XTHPImhynkibsfQg48_QzTPUW7JQzj9mgtKqnLCkDm7YCXh2G0-AuLg7hI</recordid><startdate>200409</startdate><enddate>200409</enddate><creator>Snyder, David</creator><creator>Morgan, Carl</creator><general>by the Society of Critical Care Medicine and Lippincott Williams & Wilkins</general><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200409</creationdate><title>Wide variation in cardiopulmonary resuscitation interruption intervals among commercially available automated external defibrillators may affect survival despite high defibrillation efficacy</title><author>Snyder, David ; Morgan, Carl</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3056-7e664020f095259d64759946447141712082c854de5d17ec3503deb7b56aa0903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Cardiopulmonary Resuscitation</topic><topic>Electric Countershock - instrumentation</topic><topic>Equipment Design</topic><topic>Heart Arrest - therapy</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Medical sciences</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Snyder, David</creatorcontrib><creatorcontrib>Morgan, Carl</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Critical care medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Snyder, David</au><au>Morgan, Carl</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wide variation in cardiopulmonary resuscitation interruption intervals among commercially available automated external defibrillators may affect survival despite high defibrillation efficacy</atitle><jtitle>Critical care medicine</jtitle><addtitle>Crit Care Med</addtitle><date>2004-09</date><risdate>2004</risdate><volume>32</volume><issue>9 Suppl</issue><spage>S421</spage><epage>S424</epage><pages>S421-S424</pages><issn>0090-3493</issn><eissn>1530-0293</eissn><coden>CCMDC7</coden><abstract>OBJECTIVE:Recent studies have associated interruptions of cardiopulmonary resuscitation imposed by automated external defibrillators (AEDs) with poor resuscitation outcome. In particular, the “hands-off” interval between precordial compressions and subsequent defibrillation shock has been implicated. We sought to determine the range of variation among current-generation AEDs with respect to this characteristic.
MEASUREMENTS:Seven AEDs from six manufacturers were characterized via stopwatch and arrhythmia simulator with respect to the imposed hands-off interval. All AEDs were equipped with new batteries, and measurements were repeated five times for each AED.
MAIN RESULTS:A wide variation in the hands-off interval between precordial compressions and shock delivery was observed, ranging from 5.2 to 28.4 secs, with only one AED achieving an interruption of <10 secs. Laboratory and clinical data suggest that this range of variation could be responsible for a more than two-fold variation in patient resuscitation success, an effect that far exceeds any defibrillation efficacy differences that may hypothetically exist.
CONCLUSIONS:In addition to defibrillation waveform and dose, researchers should consider the hands-off cardiopulmonary resuscitation interruption interval between cardiopulmonary resuscitation and subsequent defibrillation shock to be an important covariate of outcome in resuscitation studies. Defibrillator design should minimize this interval to avoid potential adverse consequences on patient survival.</abstract><cop>Hagerstown, MD</cop><pub>by the Society of Critical Care Medicine and Lippincott Williams & Wilkins</pub><pmid>15508671</pmid><doi>10.1097/01.CCM.0000134265.35871.2B</doi></addata></record> |
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| ispartof | Critical care medicine, 2004-09, Vol.32 (9 Suppl), p.S421-S424 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiopulmonary Resuscitation Electric Countershock - instrumentation Equipment Design Heart Arrest - therapy Humans Intensive care medicine Medical sciences Treatment Outcome |
| title | Wide variation in cardiopulmonary resuscitation interruption intervals among commercially available automated external defibrillators may affect survival despite high defibrillation efficacy |
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