Theory of Nucleosome Corkscrew Sliding in the Presence of Synthetic DNA Ligands

Histone octamers show a heat-induced mobility along DNA. Recent theoretical studies have established two mechanisms that are qualitatively and quantitatively compatible with in vitro experiments on nucleosome sliding: octamer repositioning through one-base-pair twist defects and through ten-base-pai...

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Veröffentlicht in:	Journal of molecular biology 2004-11, Vol.344 (1), p.47-58
Hauptverfasser:	Mohammad-Rafiee, Farshid, Kulić, Igor M., Schiessel, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Anisotropy Binding Sites DNA - chemistry DNA - metabolism DNA ligands DNA-Directed RNA Polymerases - metabolism Histones - metabolism Ligands Models, Biological Movement Nucleic Acid Conformation nucleosome Nucleosomes - metabolism RNA polymerase Transcription, Genetic
Online-Zugang:	Volltext
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