Heme Oxygenase-1 Induced in Muller Cells Plays a Protective Role in Retinal Ischemia-Reperfusion Injury in Rats

To investigate the protective roles played by heme oxygenase (HO)-1 and -2 in the rat retina after ischemia-reperfusion injury. Retinal ischemia was induced in rats by increasing the intraocular pressure to 110 mmHg for 60 minutes. The expression of HO-1 and -2 in the retina was determined by Wester...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2004-11, Vol.45 (11), p.4226-4232
Hauptverfasser:	Arai-Gaun, Satoko, Katai, Naomichi, Kikuchi, Takanobu, Kurokawa, Toru, Ohta, Kouichi, Yoshimura, Nagahisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blotting, Western Cell Survival Ectodysplasins Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology Heme Oxygenase (Decyclizing) - physiology Heme Oxygenase-1 Immunohistochemistry In Situ Nick-End Labeling Male Medical sciences Membrane Proteins - metabolism Neuroglia - enzymology Ophthalmology Polymerase Chain Reaction Rats Rats, Sprague-Dawley Reperfusion Injury - enzymology Reperfusion Injury - prevention & control Retinal Diseases - enzymology Retinal Diseases - prevention & control Retinopathies RNA, Messenger - metabolism RNA, Small Interfering - pharmacology S100 Proteins - metabolism Up-Regulation Vertebrates: nervous system and sense organs
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