Modulation of ovine neutrophil function and apoptosis by standardized extracts of Echinacea angustifolia, Butea frondosa and Curcuma longa

Impaired neutrophil function has been associated with increased infectious diseases in ruminants. Attachment of neutrophils to endothelium and superoxide production is critical features of their immune activity. Once the infection is cleared, programmed cell death ensures the rapid resolution of inf...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2009-04, Vol.128 (4), p.366-373
Hauptverfasser:	Farinacci, Maura, Colitti, Monica, Stefanon, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-inflammatory activity Apoptosis Apoptosis - immunology bcl-2-Associated X Protein - biosynthesis bcl-2-Associated X Protein - genetics bcl-2-Associated X Protein - immunology Butea - chemistry Butea monosperma Cell Adhesion - immunology Cell Survival - immunology Curcuma - chemistry Curcuma longa disease control drug therapy Echinacea - chemistry Echinacea angustifolia Gene expression Gene Expression Regulation - drug effects Immune function immune response immunostimulants infectious diseases inflammation interleukin-8 Interleukin-8 - biosynthesis Interleukin-8 - genetics Interleukin-8 - immunology Natural extract Neutrophil neutrophils Neutrophils - drug effects Neutrophils - immunology phytochemicals plant extracts Plant Extracts - pharmacology Proto-Oncogene Proteins c-bcl-2 - biosynthesis Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - immunology Reverse Transcriptase Polymerase Chain Reaction - veterinary RNA, Messenger - biosynthesis RNA, Messenger - genetics Ruminantia sheep Sheep - immunology sheep diseases superoxide anion Superoxides - immunology Superoxides - metabolism
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