What is your diagnosis? Lymph node cytology from a dog
: A 2‐year‐old, castrated male, mixed‐breed dog was presented to the University of Florida Veterinary Medical Center with swelling, edema, ulceration, and draining tracts in the region surrounding the left hock. The dog had mild monocytosis and moderate hyperglobulinemia. Fine‐needle aspirate specim...
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Veröffentlicht in: | Veterinary clinical pathology 2009-03, Vol.38 (1), p.91-93 |
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description | : A 2‐year‐old, castrated male, mixed‐breed dog was presented to the University of Florida Veterinary Medical Center with swelling, edema, ulceration, and draining tracts in the region surrounding the left hock. The dog had mild monocytosis and moderate hyperglobulinemia. Fine‐needle aspirate specimens of the left popliteal lymph node revealed pyogranulomatous lymphadenitis with hyphal organisms. The diameters of the hyphae were variable, ranging from 11 to 22 μm. The organism was considered as most consistent with Lagenidium caninum; although Pythium insidiosum or Lagenidium karlingii were not conclusively excluded, hyphal diameter in these organisms is typically smaller (6.6–8.8 and 2.5–11 μm, respectively). A positive Western blot confirmed the presence of serum antibodies reactive against Lagenidium sp. and the absence of antibodies to P. insidoisum, Basidiobolus, and Conidiobolus antibodies. Careful assessment of hyphal diameter in cytologic specimens may be useful in differentiating L. caninum from P. insidiosum or L. karlingii. |
doi_str_mv | 10.1111/j.1939-165X.2008.00093.x |
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Lymph node cytology from a dog</title><source>MEDLINE</source><source>Wiley Online Library Journals</source><creator>Dunbar, Mark D ; Wamsley, Heather L</creator><creatorcontrib>Dunbar, Mark D ; Wamsley, Heather L</creatorcontrib><description>: A 2‐year‐old, castrated male, mixed‐breed dog was presented to the University of Florida Veterinary Medical Center with swelling, edema, ulceration, and draining tracts in the region surrounding the left hock. The dog had mild monocytosis and moderate hyperglobulinemia. Fine‐needle aspirate specimens of the left popliteal lymph node revealed pyogranulomatous lymphadenitis with hyphal organisms. The diameters of the hyphae were variable, ranging from 11 to 22 μm. The organism was considered as most consistent with Lagenidium caninum; although Pythium insidiosum or Lagenidium karlingii were not conclusively excluded, hyphal diameter in these organisms is typically smaller (6.6–8.8 and 2.5–11 μm, respectively). A positive Western blot confirmed the presence of serum antibodies reactive against Lagenidium sp. and the absence of antibodies to P. insidoisum, Basidiobolus, and Conidiobolus antibodies. Careful assessment of hyphal diameter in cytologic specimens may be useful in differentiating L. caninum from P. insidiosum or L. karlingii.</description><identifier>ISSN: 0275-6382</identifier><identifier>EISSN: 1939-165X</identifier><identifier>DOI: 10.1111/j.1939-165X.2008.00093.x</identifier><identifier>PMID: 19228367</identifier><language>eng</language><publisher>Malden, USA: Blackwell Publishing Inc</publisher><subject>animal pathogenic fungi ; Animals ; diameter ; disease diagnosis ; dog diseases ; Dog Diseases - microbiology ; Dog Diseases - pathology ; Dogs ; Fungal ; hyphae ; Infection - veterinary ; Lagenidium ; Lagenidium - isolation & purification ; Lagenidium caninum ; Lagenidium karlingii ; lymph node cytology ; lymph nodes ; Lymph Nodes - cytology ; lymphadenitis ; Male ; mycoses ; oomycetal infection ; pathogen identification ; pets ; pseudofungal ; Pythium ; Pythium insidiosum ; serodiagnosis ; signs and symptoms (animals and humans)</subject><ispartof>Veterinary clinical pathology, 2009-03, Vol.38 (1), p.91-93</ispartof><rights>2009 American Society for Veterinary Clinical Pathology</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3893-75cd93c6cc4d7556ad8d644b0e262c91c1aba7cf046f49124c3d412ba97c00723</citedby><cites>FETCH-LOGICAL-c3893-75cd93c6cc4d7556ad8d644b0e262c91c1aba7cf046f49124c3d412ba97c00723</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1939-165X.2008.00093.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1939-165X.2008.00093.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19228367$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dunbar, Mark D</creatorcontrib><creatorcontrib>Wamsley, Heather L</creatorcontrib><title>What is your diagnosis? Lymph node cytology from a dog</title><title>Veterinary clinical pathology</title><addtitle>Vet Clin Pathol</addtitle><description>: A 2‐year‐old, castrated male, mixed‐breed dog was presented to the University of Florida Veterinary Medical Center with swelling, edema, ulceration, and draining tracts in the region surrounding the left hock. The dog had mild monocytosis and moderate hyperglobulinemia. Fine‐needle aspirate specimens of the left popliteal lymph node revealed pyogranulomatous lymphadenitis with hyphal organisms. The diameters of the hyphae were variable, ranging from 11 to 22 μm. The organism was considered as most consistent with Lagenidium caninum; although Pythium insidiosum or Lagenidium karlingii were not conclusively excluded, hyphal diameter in these organisms is typically smaller (6.6–8.8 and 2.5–11 μm, respectively). A positive Western blot confirmed the presence of serum antibodies reactive against Lagenidium sp. and the absence of antibodies to P. insidoisum, Basidiobolus, and Conidiobolus antibodies. Careful assessment of hyphal diameter in cytologic specimens may be useful in differentiating L. caninum from P. insidiosum or L. karlingii.</description><subject>animal pathogenic fungi</subject><subject>Animals</subject><subject>diameter</subject><subject>disease diagnosis</subject><subject>dog diseases</subject><subject>Dog Diseases - microbiology</subject><subject>Dog Diseases - pathology</subject><subject>Dogs</subject><subject>Fungal</subject><subject>hyphae</subject><subject>Infection - veterinary</subject><subject>Lagenidium</subject><subject>Lagenidium - isolation & purification</subject><subject>Lagenidium caninum</subject><subject>Lagenidium karlingii</subject><subject>lymph node cytology</subject><subject>lymph nodes</subject><subject>Lymph Nodes - cytology</subject><subject>lymphadenitis</subject><subject>Male</subject><subject>mycoses</subject><subject>oomycetal infection</subject><subject>pathogen identification</subject><subject>pets</subject><subject>pseudofungal</subject><subject>Pythium</subject><subject>Pythium insidiosum</subject><subject>serodiagnosis</subject><subject>signs and symptoms (animals and humans)</subject><issn>0275-6382</issn><issn>1939-165X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtOwzAQRS0EouXxC-AVu4SxnTixWCBU8ZIqgQQFdpZjO22qpC5xI5q_JyEVbJnNSDP3ztUchDCBkHR1uQyJYCIgPP4IKUAaAoBg4XYPjX8X-2gMNIkDzlI6QkfeLwFY3I0O0YgISlPGkzHi7wu1wYXHrWtqbAo1Xzlf-Gs8bav1Aq-csVi3G1e6eYvz2lVYYePmJ-ggV6W3p7t-jGZ3t6-Th2D6dP84uZkGmqWCBUmsjWCaax2ZJI65MqnhUZSBpZxqQTRRmUp0DhHPI0FopJmJCM2USDRAQtkxuhjurmv32Vi_kVXhtS1LtbKu8ZIn3eNA406YDkJdO-9rm8t1XVSqbiUB2TOTS9mjkT0a2TOTP8zktrOe7TKarLLmz7iD1AmuBsFXUdr234fl2-RZsM59Prhz5aSa14WXsxcKhAHhhPcR35j-gj8</recordid><startdate>200903</startdate><enddate>200903</enddate><creator>Dunbar, Mark D</creator><creator>Wamsley, Heather L</creator><general>Blackwell Publishing Inc</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200903</creationdate><title>What is your diagnosis? Lymph node cytology from a dog</title><author>Dunbar, Mark D ; Wamsley, Heather L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3893-75cd93c6cc4d7556ad8d644b0e262c91c1aba7cf046f49124c3d412ba97c00723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>animal pathogenic fungi</topic><topic>Animals</topic><topic>diameter</topic><topic>disease diagnosis</topic><topic>dog diseases</topic><topic>Dog Diseases - microbiology</topic><topic>Dog Diseases - pathology</topic><topic>Dogs</topic><topic>Fungal</topic><topic>hyphae</topic><topic>Infection - veterinary</topic><topic>Lagenidium</topic><topic>Lagenidium - isolation & purification</topic><topic>Lagenidium caninum</topic><topic>Lagenidium karlingii</topic><topic>lymph node cytology</topic><topic>lymph nodes</topic><topic>Lymph Nodes - cytology</topic><topic>lymphadenitis</topic><topic>Male</topic><topic>mycoses</topic><topic>oomycetal infection</topic><topic>pathogen identification</topic><topic>pets</topic><topic>pseudofungal</topic><topic>Pythium</topic><topic>Pythium insidiosum</topic><topic>serodiagnosis</topic><topic>signs and symptoms (animals and humans)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dunbar, Mark D</creatorcontrib><creatorcontrib>Wamsley, Heather L</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dunbar, Mark D</au><au>Wamsley, Heather L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>What is your diagnosis? Lymph node cytology from a dog</atitle><jtitle>Veterinary clinical pathology</jtitle><addtitle>Vet Clin Pathol</addtitle><date>2009-03</date><risdate>2009</risdate><volume>38</volume><issue>1</issue><spage>91</spage><epage>93</epage><pages>91-93</pages><issn>0275-6382</issn><eissn>1939-165X</eissn><abstract>: A 2‐year‐old, castrated male, mixed‐breed dog was presented to the University of Florida Veterinary Medical Center with swelling, edema, ulceration, and draining tracts in the region surrounding the left hock. The dog had mild monocytosis and moderate hyperglobulinemia. Fine‐needle aspirate specimens of the left popliteal lymph node revealed pyogranulomatous lymphadenitis with hyphal organisms. The diameters of the hyphae were variable, ranging from 11 to 22 μm. The organism was considered as most consistent with Lagenidium caninum; although Pythium insidiosum or Lagenidium karlingii were not conclusively excluded, hyphal diameter in these organisms is typically smaller (6.6–8.8 and 2.5–11 μm, respectively). A positive Western blot confirmed the presence of serum antibodies reactive against Lagenidium sp. and the absence of antibodies to P. insidoisum, Basidiobolus, and Conidiobolus antibodies. Careful assessment of hyphal diameter in cytologic specimens may be useful in differentiating L. caninum from P. insidiosum or L. karlingii.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>19228367</pmid><doi>10.1111/j.1939-165X.2008.00093.x</doi><tpages>3</tpages></addata></record> |
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subjects | animal pathogenic fungi Animals diameter disease diagnosis dog diseases Dog Diseases - microbiology Dog Diseases - pathology Dogs Fungal hyphae Infection - veterinary Lagenidium Lagenidium - isolation & purification Lagenidium caninum Lagenidium karlingii lymph node cytology lymph nodes Lymph Nodes - cytology lymphadenitis Male mycoses oomycetal infection pathogen identification pets pseudofungal Pythium Pythium insidiosum serodiagnosis signs and symptoms (animals and humans) |
title | What is your diagnosis? Lymph node cytology from a dog |
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