Transcriptomic profiling identifies a PU.1 regulatory network in macrophages

PU.1 is a key transcription factor for hematopoiesis and macrophage differentiation. Using chromatin immunoprecipitation we have previously identified several PU.1 target genes in macrophages and microglia. With the aim to complement these studies, we performed a transcriptomic analysis of PU.1 −/−...

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Veröffentlicht in:	Biochemical and biophysical research communications 2009-03, Vol.380 (2), p.308-312
Hauptverfasser:	Weigelt, Karin, Lichtinger, Monika, Rehli, Michael, Langmann, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ChIP-Chip Exon arrays Gene Expression Profiling Gene Regulatory Networks Macrophage differentiation Macrophages - metabolism Mice Oligonucleotide Array Sequence Analysis Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - metabolism Ptpro PU.1 PUER cells Regulatory network Trans-Activators - genetics Trans-Activators - metabolism
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