Novel interferon regulatory factor-1 polymorphisms in a Kenyan population revealed by complete gene sequencing

Variation in susceptibility to HIV-1 infection depends on numerous factors, and host genetic variation has been well-described as an important component. As a transcriptional regulator, interferon regulatory factor 1 (IRF-1) plays a key role in both innate and adaptive immunity against viral infecti...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of human genetics 2004-10, Vol.49 (10), p.528-535
Hauptverfasser:	Ji, Hezhao, Ball, Terry Blake, Kimani, Joshua, Plummer, Francis Allan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Base Sequence Biomedicine DNA-Binding Proteins - genetics Gene Expression Gene Function Gene polymorphism Gene Therapy Genetic diversity Genetics, Population HIV Human Genetics Human immunodeficiency virus Humans Insertion Interferon Interferon regulatory factor Interferon Regulatory Factor-1 Kenya Linkage Disequilibrium Molecular Medicine Molecular Sequence Data Original Article Phosphoproteins - genetics Polymorphism, Genetic Population Population genetics Promoter Regions, Genetic Single-nucleotide polymorphism Transcription
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!