Identification and characterization of a lymphocytic Rho-GTPase effector: rhotekin-2

Rhotekin belongs to the group of proteins containing a Rho-binding domain that are target peptides (effectors) for the Rho-GTPases. We previously identified a novel cDNA with homology to human rhotekin and in this study we cloned and characterized the coding region of this novel 12-exon gene. The OR...

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Veröffentlicht in:	Biochemical and biophysical research communications 2004-11, Vol.324 (4), p.1360-1369
Hauptverfasser:	Collier, F.M., Gregorio-King, C.C., Gough, T.J., Talbot, C.D., Walder, K., Kirkland, M.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Cloning, Molecular Gene Expression GTP-Binding Protein Regulators - analysis GTP-Binding Protein Regulators - genetics GTP-Binding Protein Regulators - metabolism Hematologic Neoplasms - metabolism Hematopoietic Stem Cells - metabolism Intracellular Signaling Peptides and Proteins - analysis Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Lymphocyte Activation Lymphocyte Subsets - metabolism Lymphocytes Mice Molecular Sequence Data Polymerase Chain Reaction Protein Isoforms - genetics Protein Isoforms - metabolism Rats rho GTP-Binding Proteins - metabolism Rho-GTPases Rhotekin Splice variants T-cells T-Lymphocytes - immunology T-Lymphocytes - metabolism
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