Presence of connexin 43 in subsarcolemmal, but not in interfibrillar cardiomyocyte mitochondria

Cardiomyocytes contain subsarcolemmal (SSM) and interfibrillar (IFM) mitochondria, which differ in their respiratory and calcium retention capacity. Connexin 43 (Cx43) is located at the inner membrane of SSM, and Cx43 is involved in the cardioprotection by ischemic preconditioning (IP). The function...

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Veröffentlicht in:	Basic research in cardiology 2009-03, Vol.104 (2), p.141-147
Hauptverfasser:	Boengler, Kerstin, Stahlhofen, Sabine, van de Sand, Anita, Gres, Petra, Ruiz-Meana, Marisol, Garcia-Dorado, David, Heusch, Gerd, Schulz, Rainer
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western Cardiology Connexin 43 - chemistry Connexin 43 - metabolism Connexin 43 - ultrastructure Ischemic Preconditioning, Myocardial Medicine Medicine & Public Health Mice Mice, Inbred C57BL Mitochondria, Heart - chemistry Mitochondria, Heart - metabolism Mitochondria, Heart - ultrastructure Mitochondrial Membranes - chemistry Mitochondrial Membranes - metabolism Mitochondrial Membranes - ultrastructure Myocytes, Cardiac - chemistry Myocytes, Cardiac - metabolism Myocytes, Cardiac - ultrastructure Original Contribution Rats Rats, Inbred Lew Sarcolemma - chemistry Sarcolemma - metabolism Sarcolemma - ultrastructure
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