The impact of acupuncture on in vitro fertilization outcome

Objective To replicate previous research on the efficacy of acupuncture in increasing pregnancy rates (PR) in patients undergoing IVF and to determine whether such an increase was due to a placebo effect. Design Prospective, randomized, controlled, single blind trial. Setting Private, academically a...

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Veröffentlicht in:Fertility and sterility 2009-03, Vol.91 (3), p.723-726
Hauptverfasser: Domar, Alice D., Ph.D, Meshay, Irene, A.D, Kelliher, Joseph, M.A., L.Ac, Alper, Michael, M.D, Powers, R. Douglas, Ph.D
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container_end_page 726
container_issue 3
container_start_page 723
container_title Fertility and sterility
container_volume 91
creator Domar, Alice D., Ph.D
Meshay, Irene, A.D
Kelliher, Joseph, M.A., L.Ac
Alper, Michael, M.D
Powers, R. Douglas, Ph.D
description Objective To replicate previous research on the efficacy of acupuncture in increasing pregnancy rates (PR) in patients undergoing IVF and to determine whether such an increase was due to a placebo effect. Design Prospective, randomized, controlled, single blind trial. Setting Private, academically affiliated, infertility clinic. Patient(s) One hundred fifty patients scheduled to undergo embryo transfer. Intervention(s) Subjects were randomized to either the acupuncture or control group. Acupuncture patients received the protocol, as first described by Paulus and his colleagues, for 25 minutes before and after embryo transfer. Control subjects laid quietly. All subjects then completed questionnaires on anxiety and optimism. The IVF staff remained blind to subject assignment. Main Outcome Measure(s) Clinical PRs, anxiety, optimism. Result(s) Before randomization both groups had similar demographic characteristics including age and psychological variables. There were no significant differences in PRs between the two groups. Acupuncture patients reported significantly less anxiety post-transfer and reported feeling more optimistic about their cycle and enjoyed their sessions more than the control subjects. Conclusion(s) The use of acupuncture in patients undergoing IVF was not associated with an increase in PRs but they were more relaxed and more optimistic.
doi_str_mv 10.1016/j.fertnstert.2008.01.018
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Main Outcome Measure(s) Clinical PRs, anxiety, optimism. Result(s) Before randomization both groups had similar demographic characteristics including age and psychological variables. There were no significant differences in PRs between the two groups. Acupuncture patients reported significantly less anxiety post-transfer and reported feeling more optimistic about their cycle and enjoyed their sessions more than the control subjects. 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Douglas, Ph.D</creatorcontrib><title>The impact of acupuncture on in vitro fertilization outcome</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>Objective To replicate previous research on the efficacy of acupuncture in increasing pregnancy rates (PR) in patients undergoing IVF and to determine whether such an increase was due to a placebo effect. Design Prospective, randomized, controlled, single blind trial. Setting Private, academically affiliated, infertility clinic. Patient(s) One hundred fifty patients scheduled to undergo embryo transfer. Intervention(s) Subjects were randomized to either the acupuncture or control group. Acupuncture patients received the protocol, as first described by Paulus and his colleagues, for 25 minutes before and after embryo transfer. Control subjects laid quietly. All subjects then completed questionnaires on anxiety and optimism. The IVF staff remained blind to subject assignment. 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Obstetrics</subject><subject>Humans</subject><subject>Infertility</subject><subject>Internal Medicine</subject><subject>IVF</subject><subject>Medical sciences</subject><subject>Obstetrics and Gynecology</subject><subject>placebo effect</subject><subject>Pregnancy</subject><subject>Pregnancy Rate</subject><subject>Prospective Studies</subject><subject>Sterility. 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source MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects acupuncture
Acupuncture Therapy
Adult
Anxiety - etiology
Anxiety - prevention & control
Biological and medical sciences
Birth control
Double-Blind Method
Embryo Transfer
Emotions
Female
Fertilization in Vitro - psychology
Gynecology. Andrology. Obstetrics
Humans
Infertility
Internal Medicine
IVF
Medical sciences
Obstetrics and Gynecology
placebo effect
Pregnancy
Pregnancy Rate
Prospective Studies
Sterility. Assisted procreation
Surveys and Questionnaires
Treatment Outcome
title The impact of acupuncture on in vitro fertilization outcome
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