Rosai-Dorfman disease: a case with lymphadenopathy and liver involvement

Rosai-Dorfman disease (RDD), originally described as sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic proliferative disorder with a distinctive microscopic appearance. Formerly thought to be a disease process limited to lymph nodes, RDD has now been reported in many organ syst...

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Veröffentlicht in:Journal of pediatric hematology/oncology 2009-03, Vol.31 (3), p.200-202
Hauptverfasser: Maheshwari, Anu, Seth, Anju, Choudhury, Monisha, Aggarwal, Varun, Patra, Bijoy, Aggarwal, Shilpi, Mukherjee, Sharmila B, Aneja, Satinder
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container_title Journal of pediatric hematology/oncology
container_volume 31
creator Maheshwari, Anu
Seth, Anju
Choudhury, Monisha
Aggarwal, Varun
Patra, Bijoy
Aggarwal, Shilpi
Mukherjee, Sharmila B
Aneja, Satinder
description Rosai-Dorfman disease (RDD), originally described as sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic proliferative disorder with a distinctive microscopic appearance. Formerly thought to be a disease process limited to lymph nodes, RDD has now been reported in many organ systems like bone, skin and soft tissue, central nervous system, eye and orbit, and upper respiratory tract. Here we report a case of RDD with hepatic involvement, which is even more rare.
doi_str_mv 10.1097/MPH.0b013e31818e5369
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subjects Child, Preschool
Female
Histiocytosis, Sinus - complications
Histiocytosis, Sinus - pathology
Humans
Liver Diseases - etiology
Lymph Nodes - pathology
Lymphatic Diseases - etiology
Lymphatic Diseases - pathology
Tomography, X-Ray Computed
title Rosai-Dorfman disease: a case with lymphadenopathy and liver involvement
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