Opioid receptor blockade reduces Fas‐induced hepatitis in mice

Fas (CD95)‐induced hepatocyte apoptosis and cytotoxic activity of neutrophils infiltrating the injured liver are two major events leading to hepatitis. Because it has been reported that opioids, via a direct interaction, sensitize splenocytes to Fas‐mediated apoptosis by upregulating Fas messenger R...

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Veröffentlicht in:Hepatology (Baltimore, Md.) Md.), 2004-11, Vol.40 (5), p.1136-1143
Hauptverfasser: Jaume, Martial, Jacquet, Sébastien, Cavaillès, Pierre, Macé, Gaëtane, Stephan, Lionel, Blanpied, Catherine, Demur, Cécile, Brousset, Pierre, Dietrich, Gilles
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Sprache:eng
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