Determination of cetirizine dihydrochloride, related impurities and preservatives in oral solution and tablet dosage forms using HPLC

An HPLC method was developed and validated for the determination of cetirizine dihydrochloride (CZ) as well as its related impurities in commercial oral solution and tablet formulations. Furthermore, two preservatives associated with the drug formulations, namely, propyl (PP) and butylparabens (BP)...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2004-10, Vol.36 (2), p.341-350
Hauptverfasser:	Jaber, A.M.Y., Al Sherife, H.A., Al Omari, M.M., Badwan, A.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical, structural and metabolic biochemistry Biological and medical sciences Calibration Cetirizine Cetirizine - analysis Chromatography, High Pressure Liquid Drug Contamination Drug Stability Fundamental and applied biological sciences. Psychology General pharmacology Histamine H1 Antagonists - analysis HPLC Impurities Medical sciences Pharmaceutical Solutions Pharmacology. Drug treatments Preservatives Preservatives, Pharmaceutical Reference Standards Reproducibility of Results Spectrophotometry, Ultraviolet Stability indicting Tablets
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