Gene expression profiles of inducible nitric oxide synthase and cytokines in Leishmania major-infected macrophage-like RAW 264.7 cells treated with gallic acid

Abstract The effects of gallic acid on the gene expressions of inducible nitric oxide synthase (iNOS) and the cytokines interleukin (IL)-1, IL-10, IL-12, IL-18, TNF-α, and interferon (IFN)-γ were investigated by reverse-transcription polymerase chain reaction (RT-PCR). The experiments were performed...

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Veröffentlicht in:	Planta medica 2004-10, Vol.70 (10), p.924-928
Hauptverfasser:	Radtke, O.A, Kiderlen, A.F, Kayser, O, Kolodziej, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences cell lines Cytokines - biosynthesis Cytokines - genetics DNA Primers gallic acid Gallic Acid - administration & dosage Gallic Acid - pharmacology Gallic Acid - therapeutic use Gene Expression Regulation General pharmacology Immunoassay interferons interleukin-1 interleukin-10 interleukin-12 interleukin-18 Leishmania major macrophages Macrophages - drug effects Macrophages - metabolism Medical sciences Mice molecular sequence data nitric oxide synthase Nitric Oxide Synthase - biosynthesis Nitric Oxide Synthase - genetics Nitric Oxide Synthase Type II nucleotide sequences Original Paper Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments phytochemicals Phytotherapy Plants, Medicinal Polymerase Chain Reaction RNA, Messenger - biosynthesis tumor necrosis factors
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