Hyperglycemia In Vitro Up-Regulates Growth-Related Cell Cycle Proteins of Adult Mouse Pancreatic Islets

Abstract To study effects of glucose on growth-related proteins of adult islets, we cultured mice islets in medium containing either 5.5 mmol/L (LG) or 20 mmol/L (HG) glucose. Total islet proteins were processed for sodium dodecyl sulfate polyacrylamide gel and Western blotting using antibodies agai...

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Veröffentlicht in:	Transplantation proceedings 2009, Vol.41 (1), p.339-342
Hauptverfasser:	Hsu, S, Fu, S.-H, Chen, S.-T, Hsu, B.R.-S
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - genetics Animals Biological and medical sciences Cell Division - drug effects Cyclin B - genetics Cyclin B1 Forkhead Box Protein M1 Forkhead Transcription Factors - genetics Fundamental and applied biological sciences. Psychology Fundamental immunology Glucose - pharmacology Hyperglycemia - physiopathology Islets of Langerhans - cytology Islets of Langerhans - drug effects Islets of Langerhans - physiopathology Male Medical sciences Mice Mice, Inbred C57BL Proliferating Cell Nuclear Antigen - genetics Surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology Up-Regulation
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