Differential damage and recovery of human mesenchymal stem cells after exposure to chemotherapeutic agents

Summary Mesenchymal stem cells (MSCs) are an important cellular component of the bone marrow microenvironment for supporting haemopoiesis. However, their response to high‐dose chemotherapy remains unknown. We assessed the acute direct effects of individual chemotherapeutic agents on human MSCs (hMSC...

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Veröffentlicht in:	British journal of haematology 2004-11, Vol.127 (3), p.326-334
Hauptverfasser:	Li, Jing, Law, Helen K. W., Lau, Yu Lung, Chan, Godfrey Chi Fung
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology apoptosis Apoptosis - drug effects Biological and medical sciences bone marrow microenvironment Cell Count Cell Differentiation - drug effects Cell Line Cell Proliferation - drug effects Cells, Cultured chemotherapy Dose-Response Relationship, Drug Hematologic and hematopoietic diseases Hematology Humans Immunophenotyping Medical sciences mesenchymal stem cell Mesoderm - cytology proliferation Stem Cells - cytology Stem Cells - drug effects
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