Tau Mutations in Neurodegenerative Diseases

Tau deposition is found in a variety of neurodegenerative brain diseases. The identification of tau mutations that cause familial dementia demonstrated that aberrant Tau alone could cause neurodegenerative disease and suggested that Tau likely plays a role in other cases in which Tau deposits are fo...

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Veröffentlicht in:	The Journal of biological chemistry 2009-03, Vol.284 (10), p.6021-6025
1. Verfasser:	Wolfe, Michael S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Alzheimer Disease - genetics Alzheimer Disease - metabolism Animals Humans Mice Mutation Phosphorylation - genetics tau Proteins - genetics tau Proteins - metabolism Tubulin - genetics Tubulin - metabolism
Online-Zugang:	Volltext
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