N-Acylated and N, N′-diacylated imidazolidine-2-thione derivatives and N, N′-diacylated tetrahydropyrimidine-2(1 H)-thione analogues: Synthesis and antiproliferative activity

Fifty-one acylthioureas (ATUs) incorporating imidazolidine-2-thione or its upper cyclohomologue were prepared by parallel synthesis and evaluated against a high number of human cancer cell lines for antiproliferative activity. ATUs 1o (3,5-dichlorobenzoyl), 1s (2-furoyl), 3s (2-furoyl) and 1t (2-the...

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