Q192R polymorphism of the paraoxanase 1 gene and its association with serum lipoprotein variables and carotid artery intima-media thickness in young adults from a biracial community The Bogalusa Heart Study

Paraoxanase (PON 1), a high-density lipoprotein-associated enzyme, exerts an antiatherogenic effect by protecting low-density lipoproteins (LDL) against oxidation. A common polymorphism at codon 192(Q/R) of the PON 1 gene has been shown to be associated with an adverse lipoprotein profile and increa...

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Veröffentlicht in:Atherosclerosis 2004-11, Vol.177 (1), p.167-174
Hauptverfasser: SRINIVASAN, Sathanur R, SHENGXU LI, WEI CHEN, RONG TANG, BOND, M. Gene, BOERWINKLE, Eric, BERENSON, Gerald S
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Sprache:eng
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