Protective effect of melatonin on experimental otitis media with effusion in guinea pigs

The aims of this study were: (a) to assess whether the increased oxidative stress in otitis media with effusion (OME) induced in guinea pigs by histamine injection into the middle ear cavity is reflected by lipid peroxidation in erythrocytes, plasma, and middle ear effusion fluid; (b) to survey the...

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Veröffentlicht in:	Annals of clinical and laboratory science 2004-06, Vol.34 (3), p.341-346
Hauptverfasser:	Ucuncu, Harun, Aktan, Bulent, Ozabacigil, Fatma, Buyukokuroglu, M Emin, Akyuz, Mehmet, Altas, Enver
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - therapeutic use Disease Models, Animal Erythrocytes - drug effects Erythrocytes - enzymology Guinea Pigs Histamine - pharmacology Lipid Peroxidation - drug effects Malondialdehyde - metabolism Melatonin - therapeutic use Methylprednisolone - therapeutic use Otitis Media with Effusion - metabolism Otitis Media with Effusion - pathology Otitis Media with Effusion - prevention & control Oxidative Stress - physiology Reactive Oxygen Species - metabolism
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