Expression of GABA(B) receptors is altered in brains of subjects with autism

Autism is a neurodevelopmental disorder that is often comorbid with seizures. Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in brain. GABA(B) receptors play an important role in maintaining excitatory-inhibitory balance in brain and alterations may lead to seizures. We compa...

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Veröffentlicht in:	Cerebellum (London, England) England), 2009-03, Vol.8 (1), p.64-69
Hauptverfasser:	Fatemi, S Hossein, Folsom, Timothy D, Reutiman, Teri J, Thuras, Paul D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Autistic Disorder - genetics Autistic Disorder - pathology Cerebellum - metabolism Cerebellum - pathology Child Child, Preschool Female Frontal Lobe - metabolism Frontal Lobe - pathology Humans Male Parietal Lobe - metabolism Parietal Lobe - pathology Receptors, GABA-B - genetics Receptors, GABA-B - metabolism Reference Values Young Adult
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