Effects of polyenylphosphatidylcholine on cytokines, nitrite/nitrate levels, antioxidant activity and lipid peroxidation in rats with sepsis

To determine the effect of pretreatment with polyenylphosphatidylcholine (lecithin, PPC) on plasma levels of tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, IL-10, total nitrite/nitrate (NOx), and tissue levels of superoxide dismutase (SOD) and malondialdehyde (MDA) in septic rats. Prospectiv...

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Veröffentlicht in:	Intensive care medicine 2004-10, Vol.30 (10), p.1974-1978
Hauptverfasser:	DEMIRBILEK, Semra, ERSOY, Mehmet Özcan, DEMIRBILEK, Savas, KARAMAN, Abdurrahman, AKIN, Melih, BAYRAKTAR, Mehmet, BAYRAKTAR, Nihayet
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Antioxidants Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cytokines Cytokines - blood Cytokines - drug effects Emergency and intensive care: infection, septic shock Fat Emulsions, Intravenous - pharmacology Fat Emulsions, Intravenous - therapeutic use Female Intensive care Intensive care medicine Laparotomy Lipid peroxidation Lipid Peroxidation - drug effects Lipid Peroxidation - physiology Lipids Medical schools Medical sciences Models, Animal Nitrates Nitrates - blood Nitrites - blood Oxidative stress Pharmacology. Drug treatments Phosphatidylcholines - pharmacology Phosphatidylcholines - therapeutic use Plasma Prospective Studies Random Allocation Rats Rats, Sprague-Dawley Sepsis Sepsis - blood Sepsis - physiopathology Sepsis - therapy Tumor necrosis factor-TNF
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