Inducible costimulator–positive T cells are required for allergen-induced local B-cell infiltration and antigen-specific IgE production in lung tissue

Airway inflammation plays a critical role in the pathogenesis of asthma. In susceptible individuals, airway allergen exposure results in the recruitment of inflammatory cells into lung tissue, leading to a local inflammatory response. Central to the induction and regulation of this process are T lym...

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