Crystal Engineering Approach To Forming Cocrystals of Amine Hydrochlorides with Organic Acids. Molecular Complexes of Fluoxetine Hydrochloride with Benzoic, Succinic, and Fumaric Acids

A crystal engineering strategy for designing cocrystals of pharmaceuticals is presented. The strategy increases the probability of discovering useful cocrystals and decreases the number of experiments that are needed by selecting API:guest combinations that have the greatest potential of forming ene...

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Veröffentlicht in:	Journal of the American Chemical Society 2004-10, Vol.126 (41), p.13335-13342
Hauptverfasser:	Childs, Scott L, Chyall, Leonard J, Dunlap, Jeanette T, Smolenskaya, Valeriya N, Stahly, Barbara C, Stahly, G. Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	Aliphatic, non-condensed and condensed benzenic, and alicyclic compounds Benzoic Acid - chemistry Biological and medical sciences Carboxylic Acids - chemistry Chemistry, Pharmaceutical - methods Condensed matter: structure, mechanical and thermal properties Crystallization Exact sciences and technology Fluoxetine - chemistry Fumarates - chemistry General pharmacology Hydrogen Bonding Medical sciences Models, Molecular Organic compounds Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships Physics Structure of solids and liquids crystallography Structure of specific crystalline solids Succinic Acid - chemistry X-Ray Diffraction
Online-Zugang:	Volltext
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