Should Stroke Trials Adjust Functional Outcome for Baseline Prognostic Factors?

Many stroke trials have provided neutral results. Suboptimal statistical analyses may be failing to detect effective interventions. Adjusting outcomes for baseline prognostic factors in the analysis may improve the efficiency of analysis of outcomes. Data from 23 stroke trials (25 674 patients) asse...

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Veröffentlicht in:	Stroke (1970) 2009-03, Vol.40 (3), p.888-894
Hauptverfasser:	Gray, Laura J, Bath, Philip M W, Collier, Timothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Biological and medical sciences Computer Simulation Female Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Logistic Models Male Medical sciences Middle Aged Models, Statistical Nervous system (semeiology, syndromes) Neurology Prognosis Randomized Controlled Trials as Topic Research Design Sample Size Sex Factors Stroke - epidemiology Treatment Outcome Vascular diseases and vascular malformations of the nervous system
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