Increased numbers of small circulating endothelial cells in renal cell cancer patients treated with sunitinib

Mature circulating endothelial cell (CEC) as well as endothelial progenitor populations may reflect the activity of anti-angiogenic agents on tumor neovasculature or even constitute a target for anti-angiogenic therapy. We investigated the behavior of CECs in parallel with hematopoietic progenitor c...

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Veröffentlicht in:	Angiogenesis (London) 2009-03, Vol.12 (1), p.69-79
Hauptverfasser:	Vroling, Laura, van der Veldt, Astrid A. M., de Haas, Richard R., Haanen, John B. A. G., Schuurhuis, Gerrit Jan, Kuik, Dirk J., van Cruijsen, Hester, Verheul, Henk M. W., van den Eertwegh, Alfons J. M., Hoekman, Klaas, Boven, Epie, van Hinsbergh, Victor W. M., Broxterman, Henk J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antigens, CD34 - metabolism Antineoplastic Agents - therapeutic use Biological and medical sciences Biomarkers, Tumor - blood Biomedical and Life Sciences Biomedicine Blood and lymphatic vessels Blood Cell Count Blood vessels and receptors Cancer Research Carcinoma, Renal Cell - blood Carcinoma, Renal Cell - drug therapy Cardiology Cardiology. Vascular system Cell Biology Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Endothelial Cells - cytology Endothelial Cells - drug effects Erythropoietin - blood Female Flow Cytometry Fundamental and applied biological sciences. Psychology Hematopoietic Stem Cells - drug effects Humans Indoles - pharmacology Indoles - therapeutic use Kidney Neoplasms - blood Kidney Neoplasms - drug therapy Kinetics Male Medical sciences Middle Aged Oncology Ophthalmology Original Paper Pyrroles - pharmacology Pyrroles - therapeutic use Treatment Outcome Vascular Endothelial Growth Factor A - antagonists & inhibitors Vascular Endothelial Growth Factor A - blood Vertebrates: cardiovascular system
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