Conserved regulatory elements in the promoters of two allelochemical-inducible cytochrome P450 genes differentially regulate transcription

CYP6B4, a cytochrome P450 gene from the tiger swallowtail Papilio glaucus, is transcriptionally induced in the midgut by dietary furanocoumarins, plant allelochemicals that can crosslink DNA in their UV-activated form. The CYP6B4 promoter contains an overlapping EcRE/ARE/XRE-xan element similar to t...

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Veröffentlicht in:	Insect biochemistry and molecular biology 2004-10, Vol.34 (10), p.1129-1139
Hauptverfasser:	McDonnell, Cynthia M., Brown, Rebecca Petersen, Berenbaum, May R., Schuler, Mary A.
Format:	Artikel
Sprache:	eng
Schlagworte:	allelochemicals Animals Aryl Hydrocarbon Hydroxylases - genetics Aryl hydrocarbon responses Base Sequence Benzo(a)pyrene - pharmacology benzopyrene butterflies Butterflies - drug effects Butterflies - enzymology Butterflies - genetics Conserved Sequence conserved sequences coumarins CYP6B1 promoter CYP6B4 promoter cytochrome P-450 Cytochrome P450s deletion mutants DNA - genetics Furanocoumarin responses Furocoumarins - pharmacology gene expression gene induction Genes, Insect - drug effects Insect–plant interactions metabolic detoxification methoxsalen Methoxsalen - pharmacology Molecular Sequence Data mutants Mutation Papilio Papilio glaucus Papilionidae promoter regions Promoter Regions, Genetic - drug effects psoralens reporter genes response elements Sequence Deletion Sequence Homology, Nucleic Acid transcription (genetics) Transcription, Genetic - drug effects Transcriptional regulation Transfection
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