Down-regulated expression of the TSAP6 protein in liver is associated with a transition from cirrhosis to hepatocellular carcinoma

Aims: Hepatocellular carcinoma (HCC) results from cirrhosis and, in Western Europe, hepatitis C virus and alcoholism are the predominant causes of this disease. We recently documented a global transcript repression in hepatocarcinoma nodules. The tumour suppressor activated pathway‐6 (TSAP6) transc...

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Veröffentlicht in:	Histopathology 2009-02, Vol.54 (3), p.319-327
Hauptverfasser:	Caillot, Frédérique, Daveau, Romain, Daveau, Maryvonne, Lubrano, Jean, Saint-Auret, Gaëlle, Hiron, Martine, Goria, Odile, Scotte, Michel, Francois, Arnaud, Salier, Jean-Philippe
Format:	Artikel
Sprache:	eng
Schlagworte:	alcoholism Biological and medical sciences cancer liver Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - pathology Cell Cycle Proteins cirrhosis Down-Regulation - genetics Gastroenterology. Liver. Pancreas. Abdomen Gene Expression hepatitis C Hepatitis C virus Immunohistochemistry Investigative techniques, diagnostic techniques (general aspects) Liver - metabolism Liver - pathology Liver Cirrhosis - genetics Liver Cirrhosis - pathology Liver Neoplasms - genetics Liver Neoplasms - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Oncogene Proteins - genetics Oncogene Proteins - metabolism Other diseases. Semiology Oxidoreductases Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques TSAP6
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