Sustained replication in endometrium of women with endometriosis occurs without evoking a DNA damage response

BACKGROUND To test our hypothesis that eutopic secretory phase endometrium from women with endometriosis is similar to proliferative phase endometrium from fertile women without endometriosis, we explored the expression of regulators of cell fate across the menstrual cycle. METHODS Endometrial biops...

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Veröffentlicht in:	Human reproduction (Oxford) 2009-03, Vol.24 (3), p.687-696
Hauptverfasser:	Hapangama, D.K., Turner, M.A., Drury, J.A., Quenby, S., Hart, A., Maddick, M., Martin-Ruiz, C., von Zglinicki, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Biopsy DNA Damage DNA Replication Endometriosis Endometriosis - metabolism Endometriosis - pathology endometrium Endometrium - metabolism Endometrium - pathology Female Gynecology. Andrology. Obstetrics histone γ-H2AX Histones - biosynthesis Humans Immunohistochemistry - methods Infertility - metabolism Medical sciences Middle Aged Nucleolin Phosphoproteins - biosynthesis Premenopause Proliferating Cell Nuclear Antigen - biosynthesis RNA-Binding Proteins - biosynthesis senescence Telomerase - biosynthesis Telomere - ultrastructure
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