The Host Resistance Locus sst1 Controls Innate Immunity to Listeria monocytogenes Infection in Immunodeficient Mice

Epidemiological, clinical, and experimental approaches have convincingly demonstrated that host resistance to infection with intracellular pathogens is significantly influenced by genetic polymorphisms. Using a mouse model of infection with virulent Mycobacterium tuberculosis (MTB), we have previous...

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Veröffentlicht in:	The Journal of immunology (1950) 2004-10, Vol.173 (8), p.5112-5120
Hauptverfasser:	Boyartchuk, Victor, Rojas, Mauricio, Yan, Bo-Shiun, Jobe, Ousman, Hurt, Nicholas, Dorfman, David M, Higgins, Darren E, Dietrich, William F, Kramnik, Igor
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromosome Mapping Genetic Predisposition to Disease - genetics Immunity, Innate - genetics Interferon-gamma - pharmacology Killer Cells, Natural - immunology Listeria monocytogenes Listeria monocytogenes - immunology Listeriosis - genetics Listeriosis - immunology Macrophage Activation Macrophages - microbiology Mice Mice, Inbred C3H Mice, Inbred C57BL Mice, SCID Mycobacterium tuberculosis Nitric Oxide - physiology Phagocytes - physiology Polymorphism, Genetic Reactive Oxygen Species T-Lymphocytes - immunology
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