The polymorphism Arg585Gln in the gene of the sterol regulatory element binding protein-1 (SREBP-1) is not a determinant of ketosis prone type 2 diabetes (KPD) in Africans

Abstract Aim Ketosis prone type 2 diabetes (KPD) is an atypical form of diabetes described mainly in people of sub-Saharan African origin. Its pathogenesis is unknown, although we have previously described a high prevalence of glucose-6-phosphate-dehydrogenase (G6PD) deficiency in patients with KPD....

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Veröffentlicht in:	Diabetes & metabolism 2009-02, Vol.35 (1), p.20-24
Hauptverfasser:	Choukem, S.-P, Boudou, P, Sobngwi, E, Villette, J.-M, Ibrahim, F, Moulin, P, Hadjadj, S, Eberle, D, Foufelle, F, Vexiau, P, Gautier, J.-F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African Continental Ancestry Group - genetics Amino Acid Substitution Arg585Gln Arginine Biological and medical sciences C-Peptide - blood Cross-Sectional Studies Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 2 - genetics Diabetes. Impaired glucose tolerance Diabète de type 2 cétosique Endocrine pancreas. Apud cells (diseases) Endocrinology & Metabolism Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female G6PD Glutamine Humans Insulin secretion Insulinosécrétion Internal Medicine Ketosis prone type 2 diabetes Lipids - blood Male Medical sciences Middle Aged Polymorphism, Genetic SREBF-1 Sterol Regulatory Element Binding Protein 1 - genetics
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