Regioselective Enzymatic Acylation of β-l-2‘-Deoxynucleosides:  Application in Resolution of β-d/l-2‘-Deoxynucleosides

A practical synthesis of β-l-3‘- and β-l-5‘-O-levulinyl-2‘-deoxynucleosides has been described for the first time through enzymatic acylation and/or hydrolysis processes. It is noteworthy that the different behavior exhibited by Pseudomonas cepacia lipase in the acylation of d- and l-nucleosides all...

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Veröffentlicht in:	Organic letters 2004-10, Vol.6 (21), p.3759-3762
Hauptverfasser:	García, Javier, Fernández, Susana, Ferrero, Miguel, Sanghvi, Yogesh S, Gotor, Vicente
Format:	Artikel
Sprache:	eng
Schlagworte:	Acylation Chromatography, High Pressure Liquid Enzymes - chemistry Nucleic Acid Conformation Nucleosides - chemistry
Online-Zugang:	Volltext
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