Fibulin-6 expression and anoikis in human salivary gland epithelial cells: implications in Sjogren's syndrome

Important changes in acinar and ductal morphology and function, together with pronounced extracellular matrix (ECM) remodelling, are detectable in the labial salivary glands of Sjögren's syndrome (SS) patients. The objective of this work was to determine the effect of treatment with the anti-Ro...

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Veröffentlicht in:	International immunology 2009-03, Vol.21 (3), p.303-311
Hauptverfasser:	Sisto, Margherita, D'Amore, Massimo, Lofrumento, Dario Domenico, Scagliusi, Pasquale, D’Amore, Simona, Mitolo, Vincenzo, Lisi, Sabrina
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anoikis - genetics Anoikis - immunology anti-Ro/SSA Autoantibodies - metabolism Autoantigens - immunology autoimmune Cells, Cultured dysregulation Epithelial Cells - immunology Epithelial Cells - metabolism Epithelial Cells - pathology extracellular matrix Extracellular Matrix Proteins - genetics Extracellular Matrix Proteins - immunology Extracellular Matrix Proteins - metabolism Female hemicentin Humans Immunoglobulins - genetics Immunoglobulins - immunology Immunoglobulins - metabolism Male Microscopy, Confocal Middle Aged Ribonucleoproteins - immunology RNA, Small Cytoplasmic - immunology Salivary Glands - immunology Salivary Glands - metabolism Salivary Glands - pathology Sjogren's Syndrome - immunology
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