Pentoxifylline Inhibits Tumor Necrosis Factor-Alpha Induced Synthesis of Complement Component C3 in Human Endothelial Cells

Vascular endothelium is a major target for the inflammatory damage that occurs with multiple organ dysfunction associated with sepsis and other trauma. The growing appreciation of endothelium as a target of inflammation has obscured the importance of these cells as a source of inflammatory mediators...

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