Postnatal growth in children born small and appropriate for gestational age during the first years of life
The aim of the study was to evaluate growth pattern of small- and appropriate-for-gestational-age children and to identify prenatal and postnatal risk factors for short stature and development of components of metabolic syndrome. A total of 109 small- and 239 appropriate-for-gestational-age infants...
Gespeichert in:
| Veröffentlicht in: | Medicina (Kaunas, Lithuania) Lithuania), 2009-01, Vol.45 (1), p.51-60 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng ; lit |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 60 |
|---|---|
| container_issue | 1 |
| container_start_page | 51 |
| container_title | Medicina (Kaunas, Lithuania) |
| container_volume | 45 |
| creator | Valūniene, Margarita Danylaite, Agne Kryziūte, Dovile Ramanauskaite, Giedre Lasiene, Danute Lasas, Liudvikas Verkauskiene, Rasa |
| description | The aim of the study was to evaluate growth pattern of small- and appropriate-for-gestational-age children and to identify prenatal and postnatal risk factors for short stature and development of components of metabolic syndrome. A total of 109 small- and 239 appropriate-for-gestational-age infants were enrolled in the study. Within 24 hours after birth and at 2, 5, 9, 12, 18, 24 months, and 6 years of age, anthropometric data were recorded for study children. Cord blood samples from study infants were collected, and insulin-like growth factor-1 (IGF), IGF-binding protein-3, and leptin levels were measured. Birth weight and height (P |
| doi_str_mv | 10.3390/medicina45010008 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66944934</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>66944934</sourcerecordid><originalsourceid>FETCH-LOGICAL-c269t-6b30badbde48c14154cb1ba4f581087961a38f830e9f9a590fa71f7fa5bbe9723</originalsourceid><addsrcrecordid>eNpdUMtKAzEUDaLYWt27kqzcjSaTzCNLKb6goAtdDzczyTQlTWqSQfx7Iy0oru6F8-Ccg9AlJTeMCXK7VYPpjQNeEUoIaY_QnNa8LQTl_PjPP0NnMW4IYWXVlKdoRkVZsobUc7R59TE5SGDxGPxnWmPjcL82dgjKYemDw3EL1mJwA4bdLvhdMJAU1j7gUcUEyXiX1TAqPEzBuBGndYZNiAl_KQgRe42t0eocnWiwUV0c7gK9P9y_LZ-K1cvj8_JuVfRlLVJRS0YkDHJQvO0ppxXvJZXAddVS0jaipsBa3TKihBZQCaKhobrRUEmpRFOyBbre--awH1OO2G1N7JW14JSfYlfXgnPBeCaSPbEPPsagdJe7bSF8dZR0P_t2__fNkquD9yQz-Cs4DMq-ATSHee4</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>66944934</pqid></control><display><type>article</type><title>Postnatal growth in children born small and appropriate for gestational age during the first years of life</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>Valūniene, Margarita ; Danylaite, Agne ; Kryziūte, Dovile ; Ramanauskaite, Giedre ; Lasiene, Danute ; Lasas, Liudvikas ; Verkauskiene, Rasa</creator><creatorcontrib>Valūniene, Margarita ; Danylaite, Agne ; Kryziūte, Dovile ; Ramanauskaite, Giedre ; Lasiene, Danute ; Lasas, Liudvikas ; Verkauskiene, Rasa</creatorcontrib><description>The aim of the study was to evaluate growth pattern of small- and appropriate-for-gestational-age children and to identify prenatal and postnatal risk factors for short stature and development of components of metabolic syndrome. A total of 109 small- and 239 appropriate-for-gestational-age infants were enrolled in the study. Within 24 hours after birth and at 2, 5, 9, 12, 18, 24 months, and 6 years of age, anthropometric data were recorded for study children. Cord blood samples from study infants were collected, and insulin-like growth factor-1 (IGF), IGF-binding protein-3, and leptin levels were measured. Birth weight and height (P<0.001) and insulin-like growth factor-1, IGF-binding protein-3, and leptin levels (P<0.05) were lower in children born small for gestational age vs. children born appropriate for gestational age. At 2, 5, 12, 18, and 24 months and 6 years of age, children born small for gestational age remained shorter and weighed less (P<0.001). Waist-to-hip ratio, heart rate at 6 years of age and gain in body mass index from birth up to 6 years of age was higher in children born small for gestational age. Height gain during the first year of life was mainly influenced by birth length and target height. Maternal weight before pregnancy and cord leptin levels were the most significant factors influencing postnatal weight gain during the first years of life.
During the first 6 years of life, children born small for gestational age remained shorter and lighter. A greater catch-up in body mass index and tendency towards central pattern of fat distribution during the first years of life might be predisposing factors for the development of long-term metabolic complications in these individuals.</description><identifier>ISSN: 1648-9144</identifier><identifier>EISSN: 1648-9144</identifier><identifier>DOI: 10.3390/medicina45010008</identifier><identifier>PMID: 19223706</identifier><language>eng ; lit</language><publisher>Switzerland</publisher><subject>Birth Weight ; Body Mass Index ; Chi-Square Distribution ; Child ; Child Development ; Child, Preschool ; Data Interpretation, Statistical ; Female ; Fetal Blood - chemistry ; Follow-Up Studies ; Growth Disorders - blood ; Growth Disorders - diagnosis ; Growth Disorders - epidemiology ; Growth Disorders - etiology ; Growth Disorders - metabolism ; Humans ; Infant ; Infant, Newborn ; Infant, Small for Gestational Age ; Insulin Resistance ; Insulin-Like Growth Factor Binding Protein 3 - blood ; Insulin-Like Growth Factor I - analysis ; Leptin - blood ; Male ; Mothers ; Pregnancy ; Radioimmunoassay ; Risk Factors ; Time Factors</subject><ispartof>Medicina (Kaunas, Lithuania), 2009-01, Vol.45 (1), p.51-60</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c269t-6b30badbde48c14154cb1ba4f581087961a38f830e9f9a590fa71f7fa5bbe9723</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,864,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19223706$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Valūniene, Margarita</creatorcontrib><creatorcontrib>Danylaite, Agne</creatorcontrib><creatorcontrib>Kryziūte, Dovile</creatorcontrib><creatorcontrib>Ramanauskaite, Giedre</creatorcontrib><creatorcontrib>Lasiene, Danute</creatorcontrib><creatorcontrib>Lasas, Liudvikas</creatorcontrib><creatorcontrib>Verkauskiene, Rasa</creatorcontrib><title>Postnatal growth in children born small and appropriate for gestational age during the first years of life</title><title>Medicina (Kaunas, Lithuania)</title><addtitle>Medicina (Kaunas)</addtitle><description>The aim of the study was to evaluate growth pattern of small- and appropriate-for-gestational-age children and to identify prenatal and postnatal risk factors for short stature and development of components of metabolic syndrome. A total of 109 small- and 239 appropriate-for-gestational-age infants were enrolled in the study. Within 24 hours after birth and at 2, 5, 9, 12, 18, 24 months, and 6 years of age, anthropometric data were recorded for study children. Cord blood samples from study infants were collected, and insulin-like growth factor-1 (IGF), IGF-binding protein-3, and leptin levels were measured. Birth weight and height (P<0.001) and insulin-like growth factor-1, IGF-binding protein-3, and leptin levels (P<0.05) were lower in children born small for gestational age vs. children born appropriate for gestational age. At 2, 5, 12, 18, and 24 months and 6 years of age, children born small for gestational age remained shorter and weighed less (P<0.001). Waist-to-hip ratio, heart rate at 6 years of age and gain in body mass index from birth up to 6 years of age was higher in children born small for gestational age. Height gain during the first year of life was mainly influenced by birth length and target height. Maternal weight before pregnancy and cord leptin levels were the most significant factors influencing postnatal weight gain during the first years of life.
During the first 6 years of life, children born small for gestational age remained shorter and lighter. A greater catch-up in body mass index and tendency towards central pattern of fat distribution during the first years of life might be predisposing factors for the development of long-term metabolic complications in these individuals.</description><subject>Birth Weight</subject><subject>Body Mass Index</subject><subject>Chi-Square Distribution</subject><subject>Child</subject><subject>Child Development</subject><subject>Child, Preschool</subject><subject>Data Interpretation, Statistical</subject><subject>Female</subject><subject>Fetal Blood - chemistry</subject><subject>Follow-Up Studies</subject><subject>Growth Disorders - blood</subject><subject>Growth Disorders - diagnosis</subject><subject>Growth Disorders - epidemiology</subject><subject>Growth Disorders - etiology</subject><subject>Growth Disorders - metabolism</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infant, Small for Gestational Age</subject><subject>Insulin Resistance</subject><subject>Insulin-Like Growth Factor Binding Protein 3 - blood</subject><subject>Insulin-Like Growth Factor I - analysis</subject><subject>Leptin - blood</subject><subject>Male</subject><subject>Mothers</subject><subject>Pregnancy</subject><subject>Radioimmunoassay</subject><subject>Risk Factors</subject><subject>Time Factors</subject><issn>1648-9144</issn><issn>1648-9144</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdUMtKAzEUDaLYWt27kqzcjSaTzCNLKb6goAtdDzczyTQlTWqSQfx7Iy0oru6F8-Ccg9AlJTeMCXK7VYPpjQNeEUoIaY_QnNa8LQTl_PjPP0NnMW4IYWXVlKdoRkVZsobUc7R59TE5SGDxGPxnWmPjcL82dgjKYemDw3EL1mJwA4bdLvhdMJAU1j7gUcUEyXiX1TAqPEzBuBGndYZNiAl_KQgRe42t0eocnWiwUV0c7gK9P9y_LZ-K1cvj8_JuVfRlLVJRS0YkDHJQvO0ppxXvJZXAddVS0jaipsBa3TKihBZQCaKhobrRUEmpRFOyBbre--awH1OO2G1N7JW14JSfYlfXgnPBeCaSPbEPPsagdJe7bSF8dZR0P_t2__fNkquD9yQz-Cs4DMq-ATSHee4</recordid><startdate>20090101</startdate><enddate>20090101</enddate><creator>Valūniene, Margarita</creator><creator>Danylaite, Agne</creator><creator>Kryziūte, Dovile</creator><creator>Ramanauskaite, Giedre</creator><creator>Lasiene, Danute</creator><creator>Lasas, Liudvikas</creator><creator>Verkauskiene, Rasa</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20090101</creationdate><title>Postnatal growth in children born small and appropriate for gestational age during the first years of life</title><author>Valūniene, Margarita ; Danylaite, Agne ; Kryziūte, Dovile ; Ramanauskaite, Giedre ; Lasiene, Danute ; Lasas, Liudvikas ; Verkauskiene, Rasa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c269t-6b30badbde48c14154cb1ba4f581087961a38f830e9f9a590fa71f7fa5bbe9723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; lit</language><creationdate>2009</creationdate><topic>Birth Weight</topic><topic>Body Mass Index</topic><topic>Chi-Square Distribution</topic><topic>Child</topic><topic>Child Development</topic><topic>Child, Preschool</topic><topic>Data Interpretation, Statistical</topic><topic>Female</topic><topic>Fetal Blood - chemistry</topic><topic>Follow-Up Studies</topic><topic>Growth Disorders - blood</topic><topic>Growth Disorders - diagnosis</topic><topic>Growth Disorders - epidemiology</topic><topic>Growth Disorders - etiology</topic><topic>Growth Disorders - metabolism</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infant, Small for Gestational Age</topic><topic>Insulin Resistance</topic><topic>Insulin-Like Growth Factor Binding Protein 3 - blood</topic><topic>Insulin-Like Growth Factor I - analysis</topic><topic>Leptin - blood</topic><topic>Male</topic><topic>Mothers</topic><topic>Pregnancy</topic><topic>Radioimmunoassay</topic><topic>Risk Factors</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Valūniene, Margarita</creatorcontrib><creatorcontrib>Danylaite, Agne</creatorcontrib><creatorcontrib>Kryziūte, Dovile</creatorcontrib><creatorcontrib>Ramanauskaite, Giedre</creatorcontrib><creatorcontrib>Lasiene, Danute</creatorcontrib><creatorcontrib>Lasas, Liudvikas</creatorcontrib><creatorcontrib>Verkauskiene, Rasa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Medicina (Kaunas, Lithuania)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Valūniene, Margarita</au><au>Danylaite, Agne</au><au>Kryziūte, Dovile</au><au>Ramanauskaite, Giedre</au><au>Lasiene, Danute</au><au>Lasas, Liudvikas</au><au>Verkauskiene, Rasa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Postnatal growth in children born small and appropriate for gestational age during the first years of life</atitle><jtitle>Medicina (Kaunas, Lithuania)</jtitle><addtitle>Medicina (Kaunas)</addtitle><date>2009-01-01</date><risdate>2009</risdate><volume>45</volume><issue>1</issue><spage>51</spage><epage>60</epage><pages>51-60</pages><issn>1648-9144</issn><eissn>1648-9144</eissn><abstract>The aim of the study was to evaluate growth pattern of small- and appropriate-for-gestational-age children and to identify prenatal and postnatal risk factors for short stature and development of components of metabolic syndrome. A total of 109 small- and 239 appropriate-for-gestational-age infants were enrolled in the study. Within 24 hours after birth and at 2, 5, 9, 12, 18, 24 months, and 6 years of age, anthropometric data were recorded for study children. Cord blood samples from study infants were collected, and insulin-like growth factor-1 (IGF), IGF-binding protein-3, and leptin levels were measured. Birth weight and height (P<0.001) and insulin-like growth factor-1, IGF-binding protein-3, and leptin levels (P<0.05) were lower in children born small for gestational age vs. children born appropriate for gestational age. At 2, 5, 12, 18, and 24 months and 6 years of age, children born small for gestational age remained shorter and weighed less (P<0.001). Waist-to-hip ratio, heart rate at 6 years of age and gain in body mass index from birth up to 6 years of age was higher in children born small for gestational age. Height gain during the first year of life was mainly influenced by birth length and target height. Maternal weight before pregnancy and cord leptin levels were the most significant factors influencing postnatal weight gain during the first years of life.
During the first 6 years of life, children born small for gestational age remained shorter and lighter. A greater catch-up in body mass index and tendency towards central pattern of fat distribution during the first years of life might be predisposing factors for the development of long-term metabolic complications in these individuals.</abstract><cop>Switzerland</cop><pmid>19223706</pmid><doi>10.3390/medicina45010008</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1648-9144 |
| ispartof | Medicina (Kaunas, Lithuania), 2009-01, Vol.45 (1), p.51-60 |
| issn | 1648-9144 1648-9144 |
| language | eng ; lit |
| recordid | cdi_proquest_miscellaneous_66944934 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Birth Weight Body Mass Index Chi-Square Distribution Child Child Development Child, Preschool Data Interpretation, Statistical Female Fetal Blood - chemistry Follow-Up Studies Growth Disorders - blood Growth Disorders - diagnosis Growth Disorders - epidemiology Growth Disorders - etiology Growth Disorders - metabolism Humans Infant Infant, Newborn Infant, Small for Gestational Age Insulin Resistance Insulin-Like Growth Factor Binding Protein 3 - blood Insulin-Like Growth Factor I - analysis Leptin - blood Male Mothers Pregnancy Radioimmunoassay Risk Factors Time Factors |
| title | Postnatal growth in children born small and appropriate for gestational age during the first years of life |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T22%3A12%3A28IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Postnatal%20growth%20in%20children%20born%20small%20and%20appropriate%20for%20gestational%20age%20during%20the%20first%20years%20of%20life&rft.jtitle=Medicina%20(Kaunas,%20Lithuania)&rft.au=Val%C5%ABniene,%20Margarita&rft.date=2009-01-01&rft.volume=45&rft.issue=1&rft.spage=51&rft.epage=60&rft.pages=51-60&rft.issn=1648-9144&rft.eissn=1648-9144&rft_id=info:doi/10.3390/medicina45010008&rft_dat=%3Cproquest_cross%3E66944934%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=66944934&rft_id=info:pmid/19223706&rfr_iscdi=true |