Gene Microarray Analysis of Peripheral Blood Cells in Pulmonary Arterial Hypertension

The importance of genetic predisposition, inflammation, and autoimmune mechanisms in the development of pulmonary arterial hypertension (PAH) is becoming increasingly clear. We hypothesized that the analysis of gene expression profiles from peripheral blood mononuclear cells would distinguish patien...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2004-10, Vol.170 (8), p.911-919
Hauptverfasser:	Bull, Todd M, Coldren, Christopher D, Moore, Mark, Sotto-Santiago, Sylk M, Pham, David V, Nana-Sinkam, S. Patrick, Voelkel, Norbert F, Geraci, Mark W
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Biopsy Blood & organ donations Blood Donors Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Bone marrow, stem cells transplantation. Graft versus host reaction Cytokines Female Gene expression Gene Expression Profiling Growth factors Humans Hypertension, Pulmonary - blood Hypertension, Pulmonary - genetics Infections Inflammation Intensive care medicine Intubation Leukocytes, Mononuclear - metabolism Male Medical sciences Middle Aged Oligonucleotide Array Sequence Analysis Pathogenesis Polymerase Chain Reaction Prospective Studies Pulmonary arteries Pulmonary hypertension Retrospective Studies Review boards Scleroderma Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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