Effects of trace elements on the telomere lengths of hepatocytes L-02 and hepatoma cells SMMC-7721

The effects of selenium, zinc, iron, chromium, and lead on telomere lengths of human cells have not been investigated. This article adopted flow cytometry and fluorescence in situ hybridization to investigate the impact of different elements on cellular apoptosis and telomere lengths of human hepato...

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Veröffentlicht in:	Biological trace element research 2004-09, Vol.100 (3), p.215-228
Hauptverfasser:	Liu, Qiong, Wang, Hong, Hu, Decong, Ding, Chaojian, Xu, Huibi, Tao, Deding
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - drug effects Carcinoma, Hepatocellular - drug therapy Cell Line Cell Line, Tumor Cells Chromium Chromium - pharmacology Dose-Response Relationship, Drug Fluorescent Dyes Gene therapy Hepatocytes - drug effects Humans In Situ Hybridization, Fluorescence - methods Iron - pharmacology Lead - pharmacology Liver Neoplasms - drug therapy Selenium Sodium Sodium Selenite - pharmacology Sulfates Telomerase Telomere - drug effects Telomere - genetics Trace elements Trace Elements - chemistry Trace Elements - pharmacology Zinc - pharmacology
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