Nephrogenic fibrosing dermopathy in two patients with systemic lupus erythematosus

Nephrogenic fibrosing dermopathy (NFD) is a novel fibrosing disorder of the skin with characteristic histopathology. It affects patients with impaired renal function and appears to be independent from the type of kidney disease. Its aetiopathology is unknown and presently no standard therapy exists....

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Veröffentlicht in:Lupus 2004-01, Vol.13 (8), p.609-612
Hauptverfasser: Obermoser, G, Emberger, M, Wieser, M, Zelger, B
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container_title Lupus
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creator Obermoser, G
Emberger, M
Wieser, M
Zelger, B
description Nephrogenic fibrosing dermopathy (NFD) is a novel fibrosing disorder of the skin with characteristic histopathology. It affects patients with impaired renal function and appears to be independent from the type of kidney disease. Its aetiopathology is unknown and presently no standard therapy exists. We report a patient with systemic lupus erythematosus (SLE) and glomerulonephritis who developed diffuse indurated erythematous plaques covering nearly the entire legs and trunk. She had never received dialysis. The second patient suffered from SLE and antiphospholipid syndrome related thrombotic glomerulopathy. After 10 weeks of haemodialysis she developed the same skin condition. To the best of our knowledge, these are the first reports of NFD occurring in patients with SLE.
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subjects Antiphospholipid Syndrome - complications
Female
Fibrosis
Humans
Kidney Failure, Chronic - complications
Lupus Erythematosus, Systemic - complications
Lupus Nephritis - complications
Middle Aged
Skin Diseases - complications
Skin Diseases - pathology
title Nephrogenic fibrosing dermopathy in two patients with systemic lupus erythematosus
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