Bone morphogenetic protein-2 induces the differentiation of a mesenchymal progenitor cell line, ROB-C26, into mature osteoblasts and adipocytes

Osteoblasts and adipocytes originate from common precursor cells. We examined the effects of bone morphogenetic protein-2 (BMP-2) on the molecular mechanisms governing the diametric actions of BMP-2 on simultaneous mature osteoblast and adipocyte differentiation in a clonal mesenchymal progenitor ce...

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Veröffentlicht in:Life sciences (1973) 2009-02, Vol.84 (9), p.302-310
Hauptverfasser: Kato, Shigeyuki, Kawabata, Niki, Suzuki, Naoto, Ohmura, Masako, Takagi, Minoru
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Sprache:eng
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