Complex epithelial-mesenchymal interactions modulate transforming growth factor-β expression in keloid-derived cells

Keloids are proliferative dermal growths representing a pathologic wound healing response. We have previously demonstrated that coculture of fibroblasts derived from either keloid or normal skin have an elevated proliferation rate when cocultured with keloid‐derived keratinocytes vs. normal keratino...

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Veröffentlicht in:	Wound repair and regeneration 2004-09, Vol.12 (5), p.546-556
Hauptverfasser:	Xia, Wei, Phan, Toan-Thang, Lim, Ivor J., Longaker, Michael T., Yang, George P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Base Sequence Cell Communication - physiology Cell Proliferation Cells, Cultured Epithelium - physiology Female Fibroblasts - physiology Humans Keloid - physiopathology Keratinocytes - metabolism Keratinocytes - physiology Male Mesoderm - physiology Molecular Sequence Data Probability Reverse Transcriptase Polymerase Chain Reaction RNA - analysis Sampling Studies Transforming Growth Factor beta - metabolism
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