In Situ Tissue Analysis of Neuropeptides by MALDI FTMS In-Cell Accumulation

Herein we report the first application of Fourier transform mass spectrometry for the analysis of neuropeptides directly from neuronal tissues. Sample preparation protocols and instrumentation conditions are developed to allow in situ neuropeptide analysis of the neuroendocrine organs freshly isolat...

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Veröffentlicht in:	Analytical chemistry (Washington) 2004-10, Vol.76 (19), p.5630-5640
Hauptverfasser:	Kutz, Kimberly K, Schmidt, Joshua J, Li, Lingjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Analytical chemistry Animals Brachyura - chemistry Chemistry Exact sciences and technology Fourier transforms Neuropeptides - analysis Neuropeptides - chemistry Neuropeptides - metabolism Neuropil - chemistry Neuropil - metabolism Peptides Research methodology Spectrometric and optical methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods
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