The Cost of Comorbid Depression and Pain for Individuals Diagnosed With Generalized Anxiety Disorder
Patients with generalized anxiety disorder (GAD) often have comorbid medical and psychiatric disorders and may incur higher costs. In this study, a total of 36,435 GAD patients aged 18 to 64 were identified from a claims database. Patientʼs total health care and component costs were compared between...
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Veröffentlicht in: | The journal of nervous and mental disease 2009-02, Vol.197 (2), p.136-139 |
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creator | Zhu, Baojin Zhao, Zhongyun Ye, Wenyu Marciniak, Martin D Swindle, Ralph |
description | Patients with generalized anxiety disorder (GAD) often have comorbid medical and psychiatric disorders and may incur higher costs. In this study, a total of 36,435 GAD patients aged 18 to 64 were identified from a claims database. Patientʼs total health care and component costs were compared between GAD patients with and without comorbid depression and pain using general linear models. The average total annual cost for all the GAD patients in the study was $7451. Compared with patients with GAD-only, the estimated total cost was $762 higher for GAD with depression (p < 0.001), $2989 higher for GAD with pain (p < 0.001), and $6073 higher for GAD with both depression and pain (p < 0.001). Comorbid depression and pain had significant impact on costs, especially those with pain or with both depression and pain. This suggests that an optimal strategy for GAD should take into account comorbid pain and depression. |
doi_str_mv | 10.1097/NMD.0b013e3181963486 |
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In this study, a total of 36,435 GAD patients aged 18 to 64 were identified from a claims database. Patientʼs total health care and component costs were compared between GAD patients with and without comorbid depression and pain using general linear models. The average total annual cost for all the GAD patients in the study was $7451. Compared with patients with GAD-only, the estimated total cost was $762 higher for GAD with depression (p < 0.001), $2989 higher for GAD with pain (p < 0.001), and $6073 higher for GAD with both depression and pain (p < 0.001). Comorbid depression and pain had significant impact on costs, especially those with pain or with both depression and pain. This suggests that an optimal strategy for GAD should take into account comorbid pain and depression.</description><identifier>ISSN: 0022-3018</identifier><identifier>EISSN: 1539-736X</identifier><identifier>DOI: 10.1097/NMD.0b013e3181963486</identifier><identifier>PMID: 19214050</identifier><identifier>CODEN: JNMDAN</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; Anxiety ; Anxiety Disorders - drug therapy ; Anxiety Disorders - economics ; Anxiety Disorders - epidemiology ; Anxiety disorders. Neuroses ; Biological and medical sciences ; Chi-Square Distribution ; Comorbidity ; Depression ; Depressive Disorder - drug therapy ; Depressive Disorder - economics ; Depressive Disorder - epidemiology ; Drug Costs - statistics & numerical data ; Emotional disorders ; Female ; Health Care Costs - statistics & numerical data ; Health care expenditures ; Health Resources - economics ; Health Resources - utilization ; Humans ; Insurance Claim Review ; Male ; Medical sciences ; Mental depression ; Middle Aged ; Miscellaneous ; Mood disorders ; Multivariate Analysis ; Pain ; Pain - drug therapy ; Pain - economics ; Pain - epidemiology ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Retrospective Studies ; Studies ; United States ; Utilization Review - statistics & numerical data ; Young Adult</subject><ispartof>The journal of nervous and mental disease, 2009-02, Vol.197 (2), p.136-139</ispartof><rights>2009 Lippincott Williams & Wilkins, Inc.</rights><rights>2009 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Feb 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4890-4c018787a2aeb57a8c8a280841b9774069912ef5c816f1672c64b45b47a1a90f3</citedby><cites>FETCH-LOGICAL-c4890-4c018787a2aeb57a8c8a280841b9774069912ef5c816f1672c64b45b47a1a90f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21182929$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19214050$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhu, Baojin</creatorcontrib><creatorcontrib>Zhao, Zhongyun</creatorcontrib><creatorcontrib>Ye, Wenyu</creatorcontrib><creatorcontrib>Marciniak, Martin D</creatorcontrib><creatorcontrib>Swindle, Ralph</creatorcontrib><title>The Cost of Comorbid Depression and Pain for Individuals Diagnosed With Generalized Anxiety Disorder</title><title>The journal of nervous and mental disease</title><addtitle>J Nerv Ment Dis</addtitle><description>Patients with generalized anxiety disorder (GAD) often have comorbid medical and psychiatric disorders and may incur higher costs. In this study, a total of 36,435 GAD patients aged 18 to 64 were identified from a claims database. Patientʼs total health care and component costs were compared between GAD patients with and without comorbid depression and pain using general linear models. The average total annual cost for all the GAD patients in the study was $7451. Compared with patients with GAD-only, the estimated total cost was $762 higher for GAD with depression (p < 0.001), $2989 higher for GAD with pain (p < 0.001), and $6073 higher for GAD with both depression and pain (p < 0.001). Comorbid depression and pain had significant impact on costs, especially those with pain or with both depression and pain. This suggests that an optimal strategy for GAD should take into account comorbid pain and depression.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Anxiety</subject><subject>Anxiety Disorders - drug therapy</subject><subject>Anxiety Disorders - economics</subject><subject>Anxiety Disorders - epidemiology</subject><subject>Anxiety disorders. Neuroses</subject><subject>Biological and medical sciences</subject><subject>Chi-Square Distribution</subject><subject>Comorbidity</subject><subject>Depression</subject><subject>Depressive Disorder - drug therapy</subject><subject>Depressive Disorder - economics</subject><subject>Depressive Disorder - epidemiology</subject><subject>Drug Costs - statistics & numerical data</subject><subject>Emotional disorders</subject><subject>Female</subject><subject>Health Care Costs - statistics & numerical data</subject><subject>Health care expenditures</subject><subject>Health Resources - economics</subject><subject>Health Resources - utilization</subject><subject>Humans</subject><subject>Insurance Claim Review</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Mental depression</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Mood disorders</subject><subject>Multivariate Analysis</subject><subject>Pain</subject><subject>Pain - drug therapy</subject><subject>Pain - economics</subject><subject>Pain - epidemiology</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Retrospective Studies</subject><subject>Studies</subject><subject>United States</subject><subject>Utilization Review - statistics & numerical data</subject><subject>Young Adult</subject><issn>0022-3018</issn><issn>1539-736X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkV1rFTEQhoMo9lj9ByJB0LutM0k2H5flHK2F-nFR0buQ3c16Uvckx2TXWn-9kR4sdCAzEJ53ZpiXkOcIJwhGvfn4YXMCHSD3HDUayYWWD8gKW24axeW3h2QFwFjDAfUReVLKFQAqLuAxOULDUEALKzJcbj1dpzLTNNa6S7kLA934ffalhBSpiwP97EKkY8r0PA7hVxgWNxW6Ce57TMUP9GuYt_TMR5_dFP7Uj9P4O_j5piIl5cHnp-TRWCX-2aEeky_v3l6u3zcXn87O16cXTS-0gUb0dVWllWPOd61yuteOadACO6OUAGkMMj-2vUY5olSsl6ITbSeUQ2dg5Mfk9W3ffU4_F19muwul99Pkok9LsVIabJmWFXx5D7xKS451N8ugHk-iaiskbqE-p1KyH-0-h53LNxbB_rPAVgvsfQuq7MWh99Lt_HAnOty8Aq8OgCu9m8bsYh_Kf44hamaYuZt_nabZ5_JjWq59tlvvpnlroUYLLW8YgIGaoKkPgf8F12Kc_A</recordid><startdate>200902</startdate><enddate>200902</enddate><creator>Zhu, Baojin</creator><creator>Zhao, Zhongyun</creator><creator>Ye, Wenyu</creator><creator>Marciniak, Martin D</creator><creator>Swindle, Ralph</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>200902</creationdate><title>The Cost of Comorbid Depression and Pain for Individuals Diagnosed With Generalized Anxiety Disorder</title><author>Zhu, Baojin ; Zhao, Zhongyun ; Ye, Wenyu ; Marciniak, Martin D ; Swindle, Ralph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4890-4c018787a2aeb57a8c8a280841b9774069912ef5c816f1672c64b45b47a1a90f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Anxiety</topic><topic>Anxiety Disorders - drug therapy</topic><topic>Anxiety Disorders - economics</topic><topic>Anxiety Disorders - epidemiology</topic><topic>Anxiety disorders. Neuroses</topic><topic>Biological and medical sciences</topic><topic>Chi-Square Distribution</topic><topic>Comorbidity</topic><topic>Depression</topic><topic>Depressive Disorder - drug therapy</topic><topic>Depressive Disorder - economics</topic><topic>Depressive Disorder - epidemiology</topic><topic>Drug Costs - statistics & numerical data</topic><topic>Emotional disorders</topic><topic>Female</topic><topic>Health Care Costs - statistics & numerical data</topic><topic>Health care expenditures</topic><topic>Health Resources - economics</topic><topic>Health Resources - utilization</topic><topic>Humans</topic><topic>Insurance Claim Review</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Mental depression</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Mood disorders</topic><topic>Multivariate Analysis</topic><topic>Pain</topic><topic>Pain - drug therapy</topic><topic>Pain - economics</topic><topic>Pain - epidemiology</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Retrospective Studies</topic><topic>Studies</topic><topic>United States</topic><topic>Utilization Review - statistics & numerical data</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhu, Baojin</creatorcontrib><creatorcontrib>Zhao, Zhongyun</creatorcontrib><creatorcontrib>Ye, Wenyu</creatorcontrib><creatorcontrib>Marciniak, Martin D</creatorcontrib><creatorcontrib>Swindle, Ralph</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The journal of nervous and mental disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhu, Baojin</au><au>Zhao, Zhongyun</au><au>Ye, Wenyu</au><au>Marciniak, Martin D</au><au>Swindle, Ralph</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Cost of Comorbid Depression and Pain for Individuals Diagnosed With Generalized Anxiety Disorder</atitle><jtitle>The journal of nervous and mental disease</jtitle><addtitle>J Nerv Ment Dis</addtitle><date>2009-02</date><risdate>2009</risdate><volume>197</volume><issue>2</issue><spage>136</spage><epage>139</epage><pages>136-139</pages><issn>0022-3018</issn><eissn>1539-736X</eissn><coden>JNMDAN</coden><abstract>Patients with generalized anxiety disorder (GAD) often have comorbid medical and psychiatric disorders and may incur higher costs. In this study, a total of 36,435 GAD patients aged 18 to 64 were identified from a claims database. Patientʼs total health care and component costs were compared between GAD patients with and without comorbid depression and pain using general linear models. The average total annual cost for all the GAD patients in the study was $7451. Compared with patients with GAD-only, the estimated total cost was $762 higher for GAD with depression (p < 0.001), $2989 higher for GAD with pain (p < 0.001), and $6073 higher for GAD with both depression and pain (p < 0.001). Comorbid depression and pain had significant impact on costs, especially those with pain or with both depression and pain. This suggests that an optimal strategy for GAD should take into account comorbid pain and depression.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>19214050</pmid><doi>10.1097/NMD.0b013e3181963486</doi><tpages>4</tpages></addata></record> |
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subjects | Adolescent Adult Adult and adolescent clinical studies Anxiety Anxiety Disorders - drug therapy Anxiety Disorders - economics Anxiety Disorders - epidemiology Anxiety disorders. Neuroses Biological and medical sciences Chi-Square Distribution Comorbidity Depression Depressive Disorder - drug therapy Depressive Disorder - economics Depressive Disorder - epidemiology Drug Costs - statistics & numerical data Emotional disorders Female Health Care Costs - statistics & numerical data Health care expenditures Health Resources - economics Health Resources - utilization Humans Insurance Claim Review Male Medical sciences Mental depression Middle Aged Miscellaneous Mood disorders Multivariate Analysis Pain Pain - drug therapy Pain - economics Pain - epidemiology Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Retrospective Studies Studies United States Utilization Review - statistics & numerical data Young Adult |
title | The Cost of Comorbid Depression and Pain for Individuals Diagnosed With Generalized Anxiety Disorder |
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