T cell receptor gene usage of BP180-specific T lymphocytes from patients with bullous pemphigoid and pemphigoid gestationis

BP180 is the autoantigen of different immunobullous diseases, including bullous pemphigoid (BP) and pemphigoid gestationis (PG). Previously, we demonstrated that the NC16A domain of this autoantigen harbors key epitopes of autoantibodies and T cells, indicating that it plays an essential role in the...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2004-11, Vol.113 (2), p.179-186
Hauptverfasser:	Hacker-Foegen, Mary K., Zillikens, Detlef, Giudice, George J., Lin, Mong-Shang
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Autoantigens - immunology Autoimmunity Base Sequence Biological and medical sciences BP180 Cells, Cultured Clone Cells Collagen Type XVII Epitope Mapping Epitopes, T-Lymphocyte - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology Genes, T-Cell Receptor Humans Immunopathology Medical sciences Molecular Sequence Data Non-Fibrillar Collagens - immunology Pemphigoid Pemphigoid, Bullous - immunology Polymerase Chain Reaction Receptors, Antigen, T-Cell, alpha-beta - genetics T cell receptor T-Lymphocytes - immunology
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