Overexpression of the Nuclear Receptor Coactivator AIB1 (SRC-3) during Progression of Pancreatic Adenocarcinoma

Purpose: The nuclear receptor coactivator amplified in breast cancer 1 ( AIB1 ) was found to be amplified and overexpressed in breast and some other epithelial tumors. We have reported that expression of AIB1 is rate limiting for growth factor, as well as hormone signaling. Here, we assess the invol...

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Veröffentlicht in:	Clinical cancer research 2004-09, Vol.10 (18), p.6134-6142
Hauptverfasser:	HENKE, Ralf Thorsten, HADDAD, Bassem R, SUNG EUN KIM, RONE, Janice Dalby, MANI, Aparna, JESSUP, John Milburn, WELLSTEIN, Anton, MAITRA, Anirban, RIEGEL, Anna Tate
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Animals Antineoplastic agents Biological and medical sciences Blotting, Western Carcinoma in Situ - pathology Cell Line, Tumor Disease Progression Humans Immunohistochemistry In Situ Hybridization In Situ Hybridization, Fluorescence Medical sciences Mice Mice, Nude Neoplasm Metastasis Neoplasm Transplantation Nuclear Receptor Coactivator 3 Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pharmacology. Drug treatments RNA, Messenger - metabolism Time Factors Transcription Factors - biosynthesis Transcription Factors - genetics Tumors
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