Centromere Dynamics and Chromosome Evolution in Marsupials
The eukaryotic centromere poses an interesting evolutionary paradox: it is a chromatin entity indispensable to precise chromosome segregation in all eukaryotes, yet the DNA at the heart of the centromere is remarkably variable. Its important role of spindle attachment to the kinetochore during meios...
Gespeichert in:
| Veröffentlicht in: | The Journal of heredity 2004-09, Vol.95 (5), p.375-381 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 381 |
|---|---|
| container_issue | 5 |
| container_start_page | 375 |
| container_title | The Journal of heredity |
| container_volume | 95 |
| creator | O'Neill, R. J. Eldridge, M. D. B. Metcalfe, C. J. |
| description | The eukaryotic centromere poses an interesting evolutionary paradox: it is a chromatin entity indispensable to precise chromosome segregation in all eukaryotes, yet the DNA at the heart of the centromere is remarkably variable. Its important role of spindle attachment to the kinetochore during meiosis and mitosis notwithstanding, recent studies implicate the centromere as an active player in chromosome evolution and the divergence of species. This is exemplified by centromeric involvement in translocations, fusions, inversions, and centric shifts. Often species are defined karyotypically simply by the position of the centromere on certain chromosomes. Little is known about how the centromere, either as a functioning unit of chromatin or as a specific block of repetitive DNA sequences, acts in the creation of these types of chromosome rearrangements in an evolutionary context. Macropodine marsupials (kangaroos and wallabies) offer unique insights into current theories expositing centromere emergence during karyotypic diversification and speciation. |
| doi_str_mv | 10.1093/jhered/esh063 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_66909055</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>713203481</sourcerecordid><originalsourceid>FETCH-LOGICAL-c424t-7d5fff34767b3bb950b4ef17612e83202409b34eaef529bd1cc494f8b3f3133b3</originalsourceid><addsrcrecordid>eNqFkM1rGzEUxEVoiB0nx1zL0kNuWz_p6WOVW3CcuuC0lxRKL2K1lvC63l1H2g31f18VGwd6yWlg5sc83hByQ-EzBY3TzdoFt5q6uAaJZ2RMuRS5QsQPZAzAWE4F4IhcxrgBACo0XJARFVgUSooxuZu5tg9dk0qyh31bNnUVs7JdZbN1cruYkmz-2m2Hvu7arG6zpzLEYVeX23hFzn0Sd33UCfnxOH-eLfLl9y9fZ_fLvOKM97laCe89ciWVRWu1AMudp0pS5gpkwDhoi9yVzgum7YpWFdfcFxY9UkSLE3J76N2F7mVwsTdNHSu33Zat64ZopNSgQYh3QaqYUlDQBH76D9x0Q2jTE4bqgiEyqRKUH6AqdDEG580u1E0Z9oaC-Te9OUxvDtMn_uOxdLBNsk_0ceu3wjr27s8pL8Nvk84pYRY_f5lvWlKEYmkW-BdocY7R</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>198233267</pqid></control><display><type>article</type><title>Centromere Dynamics and Chromosome Evolution in Marsupials</title><source>MEDLINE</source><source>Oxford University Press Journals All Titles (1996-Current)</source><source>EZB-FREE-00999 freely available EZB journals</source><creator>O'Neill, R. J. ; Eldridge, M. D. B. ; Metcalfe, C. J.</creator><creatorcontrib>O'Neill, R. J. ; Eldridge, M. D. B. ; Metcalfe, C. J.</creatorcontrib><description>The eukaryotic centromere poses an interesting evolutionary paradox: it is a chromatin entity indispensable to precise chromosome segregation in all eukaryotes, yet the DNA at the heart of the centromere is remarkably variable. Its important role of spindle attachment to the kinetochore during meiosis and mitosis notwithstanding, recent studies implicate the centromere as an active player in chromosome evolution and the divergence of species. This is exemplified by centromeric involvement in translocations, fusions, inversions, and centric shifts. Often species are defined karyotypically simply by the position of the centromere on certain chromosomes. Little is known about how the centromere, either as a functioning unit of chromatin or as a specific block of repetitive DNA sequences, acts in the creation of these types of chromosome rearrangements in an evolutionary context. Macropodine marsupials (kangaroos and wallabies) offer unique insights into current theories expositing centromere emergence during karyotypic diversification and speciation.</description><identifier>ISSN: 0022-1503</identifier><identifier>EISSN: 1465-7333</identifier><identifier>DOI: 10.1093/jhered/esh063</identifier><identifier>PMID: 15388765</identifier><identifier>CODEN: JOHEA8</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>Animals ; Centromere - genetics ; Chromosomes ; Chromosomes, Mammalian - genetics ; Eukaryotes ; Evolution ; Evolution, Molecular ; Gene Rearrangement - genetics ; Genetic Variation ; Karyotyping ; Marsupialia ; Marsupialia - genetics ; Marsupials</subject><ispartof>The Journal of heredity, 2004-09, Vol.95 (5), p.375-381</ispartof><rights>Copyright Oxford University Press(England) Sep/Oct 2004</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c424t-7d5fff34767b3bb950b4ef17612e83202409b34eaef529bd1cc494f8b3f3133b3</citedby><cites>FETCH-LOGICAL-c424t-7d5fff34767b3bb950b4ef17612e83202409b34eaef529bd1cc494f8b3f3133b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15388765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>O'Neill, R. J.</creatorcontrib><creatorcontrib>Eldridge, M. D. B.</creatorcontrib><creatorcontrib>Metcalfe, C. J.</creatorcontrib><title>Centromere Dynamics and Chromosome Evolution in Marsupials</title><title>The Journal of heredity</title><addtitle>J Hered</addtitle><description>The eukaryotic centromere poses an interesting evolutionary paradox: it is a chromatin entity indispensable to precise chromosome segregation in all eukaryotes, yet the DNA at the heart of the centromere is remarkably variable. Its important role of spindle attachment to the kinetochore during meiosis and mitosis notwithstanding, recent studies implicate the centromere as an active player in chromosome evolution and the divergence of species. This is exemplified by centromeric involvement in translocations, fusions, inversions, and centric shifts. Often species are defined karyotypically simply by the position of the centromere on certain chromosomes. Little is known about how the centromere, either as a functioning unit of chromatin or as a specific block of repetitive DNA sequences, acts in the creation of these types of chromosome rearrangements in an evolutionary context. Macropodine marsupials (kangaroos and wallabies) offer unique insights into current theories expositing centromere emergence during karyotypic diversification and speciation.</description><subject>Animals</subject><subject>Centromere - genetics</subject><subject>Chromosomes</subject><subject>Chromosomes, Mammalian - genetics</subject><subject>Eukaryotes</subject><subject>Evolution</subject><subject>Evolution, Molecular</subject><subject>Gene Rearrangement - genetics</subject><subject>Genetic Variation</subject><subject>Karyotyping</subject><subject>Marsupialia</subject><subject>Marsupialia - genetics</subject><subject>Marsupials</subject><issn>0022-1503</issn><issn>1465-7333</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1rGzEUxEVoiB0nx1zL0kNuWz_p6WOVW3CcuuC0lxRKL2K1lvC63l1H2g31f18VGwd6yWlg5sc83hByQ-EzBY3TzdoFt5q6uAaJZ2RMuRS5QsQPZAzAWE4F4IhcxrgBACo0XJARFVgUSooxuZu5tg9dk0qyh31bNnUVs7JdZbN1cruYkmz-2m2Hvu7arG6zpzLEYVeX23hFzn0Sd33UCfnxOH-eLfLl9y9fZ_fLvOKM97laCe89ciWVRWu1AMudp0pS5gpkwDhoi9yVzgum7YpWFdfcFxY9UkSLE3J76N2F7mVwsTdNHSu33Zat64ZopNSgQYh3QaqYUlDQBH76D9x0Q2jTE4bqgiEyqRKUH6AqdDEG580u1E0Z9oaC-Te9OUxvDtMn_uOxdLBNsk_0ceu3wjr27s8pL8Nvk84pYRY_f5lvWlKEYmkW-BdocY7R</recordid><startdate>200409</startdate><enddate>200409</enddate><creator>O'Neill, R. J.</creator><creator>Eldridge, M. D. B.</creator><creator>Metcalfe, C. J.</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7SN</scope><scope>7SS</scope><scope>7TK</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>200409</creationdate><title>Centromere Dynamics and Chromosome Evolution in Marsupials</title><author>O'Neill, R. J. ; Eldridge, M. D. B. ; Metcalfe, C. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c424t-7d5fff34767b3bb950b4ef17612e83202409b34eaef529bd1cc494f8b3f3133b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Animals</topic><topic>Centromere - genetics</topic><topic>Chromosomes</topic><topic>Chromosomes, Mammalian - genetics</topic><topic>Eukaryotes</topic><topic>Evolution</topic><topic>Evolution, Molecular</topic><topic>Gene Rearrangement - genetics</topic><topic>Genetic Variation</topic><topic>Karyotyping</topic><topic>Marsupialia</topic><topic>Marsupialia - genetics</topic><topic>Marsupials</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>O'Neill, R. J.</creatorcontrib><creatorcontrib>Eldridge, M. D. B.</creatorcontrib><creatorcontrib>Metcalfe, C. J.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of heredity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>O'Neill, R. J.</au><au>Eldridge, M. D. B.</au><au>Metcalfe, C. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Centromere Dynamics and Chromosome Evolution in Marsupials</atitle><jtitle>The Journal of heredity</jtitle><addtitle>J Hered</addtitle><date>2004-09</date><risdate>2004</risdate><volume>95</volume><issue>5</issue><spage>375</spage><epage>381</epage><pages>375-381</pages><issn>0022-1503</issn><eissn>1465-7333</eissn><coden>JOHEA8</coden><abstract>The eukaryotic centromere poses an interesting evolutionary paradox: it is a chromatin entity indispensable to precise chromosome segregation in all eukaryotes, yet the DNA at the heart of the centromere is remarkably variable. Its important role of spindle attachment to the kinetochore during meiosis and mitosis notwithstanding, recent studies implicate the centromere as an active player in chromosome evolution and the divergence of species. This is exemplified by centromeric involvement in translocations, fusions, inversions, and centric shifts. Often species are defined karyotypically simply by the position of the centromere on certain chromosomes. Little is known about how the centromere, either as a functioning unit of chromatin or as a specific block of repetitive DNA sequences, acts in the creation of these types of chromosome rearrangements in an evolutionary context. Macropodine marsupials (kangaroos and wallabies) offer unique insights into current theories expositing centromere emergence during karyotypic diversification and speciation.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>15388765</pmid><doi>10.1093/jhered/esh063</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1503 |
| ispartof | The Journal of heredity, 2004-09, Vol.95 (5), p.375-381 |
| issn | 0022-1503 1465-7333 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_66909055 |
| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); EZB-FREE-00999 freely available EZB journals |
| subjects | Animals Centromere - genetics Chromosomes Chromosomes, Mammalian - genetics Eukaryotes Evolution Evolution, Molecular Gene Rearrangement - genetics Genetic Variation Karyotyping Marsupialia Marsupialia - genetics Marsupials |
| title | Centromere Dynamics and Chromosome Evolution in Marsupials |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T18%3A04%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Centromere%20Dynamics%20and%20Chromosome%20Evolution%20in%20Marsupials&rft.jtitle=The%20Journal%20of%20heredity&rft.au=O'Neill,%20R.%20J.&rft.date=2004-09&rft.volume=95&rft.issue=5&rft.spage=375&rft.epage=381&rft.pages=375-381&rft.issn=0022-1503&rft.eissn=1465-7333&rft.coden=JOHEA8&rft_id=info:doi/10.1093/jhered/esh063&rft_dat=%3Cproquest_cross%3E713203481%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=198233267&rft_id=info:pmid/15388765&rfr_iscdi=true |